Zebrafish as a model system for studying neuronal circuits and behavior

被引:91
|
作者
Fetcho, JR [1 ]
Liu, KS [1 ]
机构
[1] SUNY Stony Brook, Dept Neurobiol & Behav, Stony Brook, NY 11794 USA
来源
NEURONAL MECHANISMS FOR GENERATING LOCOMOTOR ACTIVITY | 1998年 / 860卷
关键词
D O I
10.1111/j.1749-6632.1998.tb09060.x
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Zebrafish are best known as a model system for studies of the genetics of development. They do, however, also offer many advantages for the study of neuronal circuitry because the larvae are transparent, allowing optical studies of neuronal activity and noninvasive photoablations of individual neurons. The combination of these optical methods with genetics through the use of mutant and transgenic lines of fish should make the zebrafish model a unique and powerful one among vertebrates. Here we review the strengths of the model and the possibilities it offers for studies of the neural basis of behavior.
引用
收藏
页码:333 / 345
页数:13
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