Steroidal glycosides from the bulbs of Allium jesdianum

被引：53

作者：

Mimaki, Y ^{[1
]}

Kuroda, M ^{[1
]}

Fukasawa, T ^{[1
]}

Sashida, Y ^{[1
]}

机构：

[1] Tokyo Univ Pharm & Life Sci, Sch Pharm, Tokyo 1920392, Japan

来源：

JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 01期

关键词：

D O I：

10.1021/np980346b

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Phytochemical analysis of the fresh bulbs of Allium jesdianum yielded four steroidal glycosides, (22S)-cholest-5-ene-1 beta, 3 beta,16 beta,22-tetrol 1,16- di-O-beta-D-glucopyranoside (1), (22S)-cholest-5-ene-1 beta,3 beta,16 beta,22-tetrol 1-O-alpha-L-rhamnopyranosyl 16-O-beta-D-glucopyranoside (2), (25R)-5 alpha-spirostane-2 alpha,3 beta-diol 3-O-{O-beta-D-glucopyranosyl-(1-->2)-O-[beta-D-xylopyranosyl-(1-->3)]-O-beta-D-glucopyranosyl-(1-->4)-beta-D-galactopyranoside} (F-gitonin) (3), and (25R)-5 alpha-spirostane-2 alpha,3 beta,6 alpha-triol 3-O-{O-beta-D-glucopyranosyl-(1-->2)-O-[beta-D-xylopyranosyl-(1-->3)]-O-beta-D-glucopyranosyl-(1-->4)-beta-D-galactopyranoside} (4). Compound 2 is a new natural product, and 4 is a new spirostanol saponin. Compound 3 was found to exhibit cytostatic and cytotoxic activities against several malignant tumor cells.

引用

页码：194 / 197

页数：4

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