Pediatric soft tissue sarcomas

被引：88
作者：
Loeb, David M. [1 ]
Thornton, Katherine [1 ]
Shokek, Ori [1 ]
机构：
[1] Johns Hopkins Univ, Sidney Kimmel Comprehens Canc Ctr, Musculoskeletal Tumor Program, Baltimore, MD 21231 USA
来源：
SURGICAL CLINICS OF NORTH AMERICA | 2008年 / 88卷 / 03期
关键词：
D O I：
10.1016/j.suc.2008.03.008
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
Soft tissue sarcomas in children are rare. Approximately 850 to 900 children and adolescents are diagnosed each year with rhabdomyosarcoma (RMS) or a non-RMS soft tissue sarcoma (NRSTS). RMS is more common in children 14 years old and younger and NRSTS in adolescents and young adults. Infants get NRSTS, but their tumors constitute a distinctive set of histologies. Surgery is a major therapeutic modality and radiation plays a role. RMS is treated with adjuvant chemotherapy, whereas chemotherapy is reserved for the NRSTS that are high grade or unresectable. This review discusses the etiology, biology, and treatment of pediatric soft tissue sarcomas.
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页码：615 / +
页数：14
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