Modification of polysaccharides: Pharmaceutical and tissue engineering applications with commercial utility (patents)

被引：37

作者：

Malviya, Rishabha ^{[1
,2
]}

Sharma, Pramod Kumar ^{[1
]}

Dubey, Susheel Kumar ^{[3
]}

机构：

[1] Galgotias Univ, Polymer Sci Lab, Dept Pharm, Sch Med & Allied Sci, Plot 2,Sect 17-A,Yamuna Expressway, Greator Noida, Up, India

[2] Uttarkhand Tech Univ, Dept Pharm, Dehra Dun, Uttarkhand, India

[3] Siddarth Inst Pharm, Dehra Dun, Uttarkhand, India

来源：

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | 2016年 / 68卷

关键词：

Modified polymer; Co-polymer; Grafting; Drug delivery; Tissue engineering; Scaffolds; Patent; MICROWAVE-ASSISTED SYNTHESIS; MODIFIED GUAR GUM; LOCUST BEAN GUM; GELLAN-GUM; WATER-RETENTION; GRAFT COPOLYMER; FLOCCULATION CHARACTERISTICS; MECHANICAL-PROPERTIES; SUCCINIC ANHYDRIDE; CONTROLLED-RELEASE;

D O I：

10.1016/j.msec.2016.06.093

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Polymer modifications open new era for the development of polymers with requisite properties. Use of modified polymers is practically boundless. Different studies focus on biomedical applications of chemically modified polysaccharides. Development and utilization of modified polysaccharides get attention to be used as carrier for pharmaceutical drug delivery as well as tissue engineering scaffolds. Grafted polymer shows better cellular regeneration, signal transmission, diagnostic and imaging material than putative form. This review article aims to discuss various approaches to modify naturally derived polymer and their applications as pharmaceutical drug carrier and as a material for wound dressing and artificial cartilage due to better biophysical cues. Manuscript included various patents based on the applications of modified polymers and techniques used to modify polymers. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：929 / 938

页数：10

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