A Multicenter Retrospective Review of Pediatric Leydig Cell Tumor of the Testis

被引：12

作者：

Luckie, Taylor M. ^{[1
]}

Danzig, Matthew ^{[5
]}

Zhou, Shengmei ^{[6
]}

Wu, Hao ^{[1
,2
,3
]}

Cost, Nicholas G. ^{[5
]}

Karaviti, Lefkothea ^{[4
]}

Venkatramani, Rajkumar ^{[1
]}

机构：

[1] Baylor Coll Med, Rare Tumors Program, Texas Childrens Canc Ctr, Houston, TX 77030 USA

[2] Baylor Coll Med, Dept Pathol & Immunol, Houston, TX 77030 USA

[3] Texas Childrens Hosp, Houston, TX 77030 USA

[4] Texas Childrens Hosp, Div Pediat Endocrinol & Metab, Houston, TX 77030 USA

[5] Univ Colorado, Sch Med, Div Urol, Dept Surg, Aurora, CO USA

[6] Childrens Hosp Los Angeles, Dept Pathol & Lab Med, Los Angeles, CA 90027 USA

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2019年 / 41卷 / 01期

关键词：

Leydig cell tumor; enucleation; precocious puberty; PRECOCIOUS PUBERTY; FOLLOW-UP; CHILDREN; BOY; ADOLESCENT; SECONDARY;

D O I：

10.1097/MPH.0000000000001124

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Leydig cell tumors (LCTs) are rare tumors arising from testosterone-producing Leydig cells. Although LCTs are usually benign, malignancy has been reported in 10% of cases in adults, and local recurrence or metachronous tumors of the contralateral testis have been described. Radical orchiectomy is the current standard of care. We report on 12 children with LCT at 3 institutions between 2000 and 2016. Presenting symptoms included precocious puberty, palpable testicular mass, and scrotal swelling. Radical orchiectomy was performed in 9 patients. Three patients were treated with enucleation. All patients were alive at last follow-up without evidence of local recurrence or metastasis.

引用

页码：74 / 76

页数：3

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