DIAGNOSTIC PERFORMANCE OF CONTRAST-ENHANCED ULTRASOUND FOR OVARIAN CANCER: A META-ANALYSIS

被引：21

作者：

Wu, Ying ^{[1
]}

Peng, Hongling ^{[1
]}

Zhao, Xia ^{[1
]}

机构：

[1] Sichuan Univ, West China Hosp 2, Dept Gynecol & Obstet, Chengdu 610041, Peoples R China

来源：

ULTRASOUND IN MEDICINE AND BIOLOGY | 2015年 / 41卷 / 04期

关键词：

Contrast-enhanced ultrasound; Diagnosis; Ovarian cancer; Meta-analysis; TUMOR ANGIOGENESIS; BENIGN; AGENT; MASSES; DIFFERENTIATION; MICROBUBBLES; SONOGRAPHY; THERAPY; GENE;

D O I：

10.1016/j.ultrasmedbio.2014.11.018

中图分类号：

O42 [声学];

学科分类号：

070206 ; 082403 ;

摘要：

This meta-analysis is the first study aimed at assessing the overall diagnostic performance of contrast-enhanced ultrasound for ovarian cancer. PubMed, Embase and Medline databases were systematically searched for relevant articles published up to June 2014. Data were pooled to yield summary sensitivity, specificity, diagnostic odds ratio and receiver operating characteristic curves using Meta-Disc Version 1.4 software. Ten independent studies with 579 ovarian tumors were enrolled in this meta-analysis. The pooled sensitivity, specificity and diagnostic odds ratio statistics were 0.89 (0.83-0.94), 0.91 (0.88-0.93) and 91.70 (41.41-203.05), respectively, and the area under the summary receiver operating characteristic curve was 0.9619 (standard error: 0.0125), all indicating that contrast-enhanced ultrasound has high diagnostic accuracy in differentiation of malignant from benign ovarian tumors. (C) 2015 World Federation for Ultrasound in Medicine & Biology.

引用

页码：967 / 974

页数：8

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