The Hammersmith hospital hematopathology case of the month: hemophagocytic lymphohistiocytosis secondary to Epstein-Barr virus associated T-cell lymphoma

被引：3
|
作者：
Krishna, Rajesh [1 ]
Byrne, Elizabeth [2 ]
Burbridge, Janine [3 ]
Salooja, Nina [1 ]
Naresh, Kikkeri N. [2 ]
机构：
[1] Imperial Coll Healthcare NHS Trust, Dept Haematol, London, England
[2] Imperial Coll Healthcare NHS Trust, Dept Histopathol, London, England
[3] N W London Hosp NHS Trust, Kennedy Galton Ctr, N W Thames Reg Genet Serv, Harrow, Middx, England
来源：
LEUKEMIA & LYMPHOMA | 2011年 / 52卷 / 06期
关键词：
Cytogenetics; lymphoma and Hodgkin disease; morphology; infectious complications; SPECTRUM; PATIENT; DISEASE;
D O I：
10.3109/10428194.2011.563888
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
We discuss the clinical presentation, investigations carried out, and the management issues in an elderly patient with hemophagocytic lymphohistiocytosis (HLH). The HLH was associated with an underlying Epstein-Barr virus positive peripheral T-cell lymphoma, not otherwise specified, and the lymphomatous cells harbored translocation t(5;9)(q11.2:p24). The 9p24 region contains the JAK2 gene. The disease had a fulminant course.
引用
收藏
页码：1127 / 1132
页数：6
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