The Hammersmith hospital hematopathology case of the month: hemophagocytic lymphohistiocytosis secondary to Epstein-Barr virus associated T-cell lymphoma

被引：3

作者：

Krishna, Rajesh ^{[1
]}

Byrne, Elizabeth ^{[2
]}

Burbridge, Janine ^{[3
]}

Salooja, Nina ^{[1
]}

Naresh, Kikkeri N. ^{[2
]}

机构：

[1] Imperial Coll Healthcare NHS Trust, Dept Haematol, London, England

[2] Imperial Coll Healthcare NHS Trust, Dept Histopathol, London, England

[3] N W London Hosp NHS Trust, Kennedy Galton Ctr, N W Thames Reg Genet Serv, Harrow, Middx, England

来源：

LEUKEMIA & LYMPHOMA | 2011年 / 52卷 / 06期

关键词：

Cytogenetics; lymphoma and Hodgkin disease; morphology; infectious complications; SPECTRUM; PATIENT; DISEASE;

D O I：

10.3109/10428194.2011.563888

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We discuss the clinical presentation, investigations carried out, and the management issues in an elderly patient with hemophagocytic lymphohistiocytosis (HLH). The HLH was associated with an underlying Epstein-Barr virus positive peripheral T-cell lymphoma, not otherwise specified, and the lymphomatous cells harbored translocation t(5;9)(q11.2:p24). The 9p24 region contains the JAK2 gene. The disease had a fulminant course.

引用

页码：1127 / 1132

页数：6

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