Low-Dose Budesonide/Formoterol Counteracts Airway Inflammation and Improves Lung Function in Chronic Obstructive Pulmonary Disease

被引：7

作者：

Hakim, Amir ^{[1
]}

Khan, Younis ^{[1
]}

Esteban, Ignacio ^{[1
]}

Meah, Sally ^{[1
]}

Miller-Larsson, Anna ^{[2
]}

Barnes, Peter J. ^{[1
]}

Usmani, Omar S. ^{[1
]}

机构：

[1] Imperial Coll London, London, England

[2] AstraZeneca Gothenburg, Molndal, Sweden

来源：

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 2019年 / 199卷 / 05期

关键词：

EXACERBATIONS;

D O I：

10.1164/rccm.201808-1590LE

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

引用

页码：662 / 664

页数：3

共 10 条

[1]

Adcock Ian M., 2002, Journal of Allergy and Clinical Immunology, V110, pS261, DOI 10.1067/mai.2002.129705

[2] Incident Pneumonia and Mortality in Patients with Chronic Obstructive Pulmonary Disease A Double Effect of Inhaled Corticosteroids? [J].

Festic, Emir ;

Scanlon, Paul D. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2015, 191 (02) :141-148

[3] Effects of a single inhaled budesonide/formoterol dose on glucocorticoid receptor activity in sputum of COPD patients [J].

Hakim, Amir ;

Khan, Younis ;

Esteban, Ignacio ;

Miller-Larsson, Anna ;

Barnes, Peter ;

Usmani, Omar .

EUROPEAN RESPIRATORY JOURNAL, 2016, 48

[4] Corticosteroid Resistance and Novel Anti-Inflammatory Therapies in Chronic Obstructive Pulmonary Disease Current Evidence and Future Direction [J].

Hakim, Amir ;

Adcock, Ian M. ;

Usmani, Omar S. .

DRUGS, 2012, 72 (10) :1299-1312

[5] Inhaled long-acting β2 agonists enhance glucocorticoid receptor nuclear translocation and efficacy in sputum macrophages in COPD [J].

Haque, Rubaiyat ;

Hakim, Amir ;

Moodley, Thunicia ;

Torrego, Alfonso ;

Essilfie-Quaye, Sarah ;

Jazrawi, Elen ;

Johnson, Malcolm ;

Barnes, Peter J. ;

Adcock, Ian M. ;

Usmani, Omar Sharif .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2013, 132 (05) :1166-1173

[6] Combination of budesonide/formoterol more effective than fluticasone/salmeterol in preventing exacerbations in chronic obstructive pulmonary disease: the PATHOS study [J].

Larsson, K. ;

Janson, C. ;

Lisspers, K. ;

Jorgensen, L. ;

Stratelis, G. ;

Telg, G. ;

Stallberg, B. ;

Johansson, G. .

JOURNAL OF INTERNAL MEDICINE, 2013, 273 (06) :584-594

[7] Withdrawal of Inhaled Glucocorticoids and Exacerbations of COPD [J].

Magnussen, Helgo ;

Disse, Bernd ;

Rodriguez-Roisin, Roberto ;

Kirsten, Anne ;

Watz, Henrik ;

Tetzlaff, Kay ;

Towse, Lesley ;

Finnigan, Helen ;

Dahl, Ronald ;

Decramer, Marc ;

Chanez, Pascal ;

Wouters, Emiel F. M. ;

Calverley, Peter M. A. ;

Chia, M. ;

Peters, M. ;

Polasek, J. ;

Sajkov, D. ;

Seale, P. ;

Wheatley, J. ;

Bedert, L. ;

Driesen, P. ;

Fievez, P. ;

Flemale, A. ;

Martinot, J-B ;

Mentens, Y. ;

Ninane, V ;

Peche, R. ;

Plas, B. ;

van Zandweghe, L. ;

Adalberto, R. ;

Carmo Moreira, M. A. ;

Fritscher, C. ;

Gondim, H. ;

Jardim, J. R. B. ;

Dancheva, A. ;

Kostov, K. ;

Lllieva-Fartunova, V ;

Metev, H. ;

Osmanliev, D. ;

Palaveev, Rashkov K. ;

Taseva, M. ;

Troshanova, E. ;

Bai, C. ;

Baiqiang, C. ;

Li, H. ;

Lin, Y. ;

Tang, Y. ;

Wu, Y. ;

Xin, J. ;

Yao, W. .

NEW ENGLAND JOURNAL OF MEDICINE, 2014, 371 (14) :1285-1294

[8] Effect of Fluticasone Furoate and Vilanterol on Exacerbations of Chronic Obstructive Pulmonary Disease in Patients with Moderate Airflow Obstruction [J].

Martinez, Fernando J. ;

Vestbo, Jorgen ;

Anderson, Julie A. ;

Brooke, Robert D. ;

Celli, Bartolome R. ;

Cowans, Nicholas J. ;

Crim, Courtney ;

Dransfield, Mark ;

Kilbride, Sally ;

Yates, Julie ;

Newby, David E. ;

Niewoehner, Dennis ;

Calverley, Peter M. A. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2017, 195 (07) :881-888

[9] A proposal for the withdrawal of inhaled corticosteroids in the clinical practice of chronic obstructive pulmonary disease [J].

Miravitlles, Marc ;

Cosio, Borja G. ;

Arnedillo, Aurelio ;

Calle, Myriam ;

Alcazar-Navarrete, Bernardino ;

Gonzalez, Cruz ;

Esteban, Cristobal ;

Antonio Trigueros, Juan ;

Rodriguez Gonzalez-Moro, Jose Miguel ;

Quintano Jimenez, Jose Antonio ;

Baloira, Adolfo .

RESPIRATORY RESEARCH, 2017, 18

[10] Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report [J].

Vogelmeier, Claus F. ;

Criner, Gerard J. ;

Martinez, Fernando J. ;

Anzueto, Antonio ;

Barnes, Peter J. ;

Bourbeau, Jean ;

Celli, Bartolome R. ;

Chen, Rongchang ;

Decramer, Marc ;

Fabbri, Leonardo M. ;

Frith, Peter ;

Halpin, David M. G. ;

Varela, M. Victorina Lopez ;

Nishimura, Masaharu ;

Roche, Nicolas ;

Rodriguez-Roisin, Roberto ;

Sin, Don D. ;

Singh, Dave ;

Stockley, Robert ;

Vestbo, Jurgen ;

Wedzicha, Jadwiga A. ;

Agusti, Alvar .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2017, 195 (05) :557-582

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