Highly Regioselective Synthesis of 1,3-Diiodonaphthalene Derivatives via a Sequential Cascade Iodocyclization

被引：42
作者：
Wang, Li-Jing
Zhu, Hai-Tao
Lu, Lei
Yang, Fang
Liu, Xue-Yuan
Liang, Yong-Min [1 ]
机构：
[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
来源：
ORGANIC LETTERS | 2012年 / 14卷 / 08期
基金：
美国国家科学基金会;
关键词：
MEDIATED ELECTROPHILIC CYCLIZATION; SUBSTITUTED QUINOLINES; EFFICIENT SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; 5-ENDO-DIG CYCLIZATIONS; INDENE DERIVATIVES; BETA-IODOFURANS; ALPHA-PYRONES; ALKYNES; ISOQUINOLINES;
D O I：
10.1021/ol300457c
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel and flexible sequentially cascade iodocyclization for the synthesis of highly substituted 1,3-diiodinated naphthalene derivatives in up to 99% yield under mild conditions is reported. The dihalogenated moiety can be readily introduced into the naphthalenes in a position that is usually not easily functionalized.
引用
收藏
页码：1990 / 1993
页数：4
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