Synthesis, characteristics and evaluation of a new monolithic silica column prepared from copolymer pluronic F127

被引：8

作者：

Yang, Gengliang ^{[1
,2
]}

Li, Fengxin ^{[1
]}

Wang, Lijuan ^{[1
]}

Row, Kyung Ho ^{[3
]}

Liu, Haiyan ^{[1
]}

Bai, Ligai ^{[1
]}

Cao, Weimin ^{[1
]}

Zhu, Tao ^{[1
]}

机构：

[1] Hebei Univ, Coll Pharm, Baoding 071002, Peoples R China

[2] Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China

[3] Inha Univ, Ctr Adv Bioseparat Technol, Dept Chem Engn, Inchon 402751, South Korea

来源：

CHROMATOGRAPHIA | 2008年 / 68卷 / 1-2期

基金：

中国国家自然科学基金;

关键词：

column liquid chromatography; normal phase separations; monolithic silica columns; copolymer Pluronic F127;

D O I：

10.1365/s10337-008-0663-x

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Monolithic silica columns were prepared via a sol-gel process using tri-block copolymer Pluronic F127 as structure-directing reagent. In this reaction, F127 induced phase separation but also acted as a template leading to a continuous structure of silica skeletons and textural pores as well as the formation of mesopores. The morphology of the monolithic materials was studied by scanning electron microscopy. The capability of separation and loading on this column were demonstrated. Phosphatidylcholine was separated from soy lecithin, demonstrating fast and efficient performance when the column was used for normal phase liquid chromatography.

引用

页码：27 / 31

页数：5