Impact of reduced tigecycline susceptibility on clinical outcomes of Acinetobacter bacteremia

被引：3
|
作者：
Chang, Yea-Yuan [1 ,2 ,3 ]
Liu, Yuag-Meng [4 ]
Liu, Chang-Pan [5 ]
Kuo, Shu-Chen [3 ,6 ]
Chen, Te-Li [3 ,7 ]
机构：
[1] Natl Yang Ming Univ Hosp, Dept Med, Div Infect Dis, Yilan, Taiwan
[2] Natl Yang Ming Univ, Inst Clin Med, Taipei, Taiwan
[3] Taipei Vet Gen Hosp, Dept Med, Div Infect Dis, Taipei, Taiwan
[4] Changhua Christian Hosp, Dept Internal Med, Div Infect Dis, Changhua, Taiwan
[5] MacKay Mem Hosp, Dept Internal Med, Div Infect Dis, Taipei, Taiwan
[6] Natl Hlth Res Inst, Natl Inst Infect Dis & Vaccinol, 35 Keyan Rd, Zhunan Town 350, Miaoli County, Taiwan
[7] Natl Def Med Ctr, Grad Inst Life Sci, Taipei, Taiwan
来源：
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION | 2018年 / 51卷 / 01期
关键词：
Tigecycline; Acinetobacter bacteremia; Minimum inhibitory concentration; Appropriate antibiotics; PROGRAM;
D O I：
10.1016/j.jmii.2017.08.024
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The higher 14-day mortality rate for patients with Acinetobacter bacteremia receiving tigecycline appropriately compared to other appropriate antibiotics (36.4% versus 14.2%, P = 0.028) was due to the poor effect of tigecycline for isolates with a minimum inhibitory concentration of 2 mg/mL (63.6% of 11 versus 14.2% of 127, P = 0.001). Copyright (C) 2017, Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC.
引用
收藏
页码：148 / 152
页数：5
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