Synthesis of novel thiopyrimidines: an investigation of anti-tubercular and antimicrobial activity

被引：12
|
作者：
Haveliwala, Dhaval D. [1 ]
Kamdar, Nimesh R. [1 ]
Mistry, Prashant T. [1 ]
Patel, Saurabh K. [1 ]
机构：
[1] Veer Narmad S Gujarat Univ, Dept Chem, Surat 395007, Gujarat, India
来源：
JOURNAL OF SULFUR CHEMISTRY | 2011年 / 32卷 / 05期
关键词：
thiopyrimidines; dithiopyrimidines; chromone; anti-tubercular activity; antimicrobial activity; PYRIDINE; DERIVATIVES;
D O I：
10.1080/17415993.2010.523894
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A variety of novel sulfur-containing tricyclic pyrimidine derivatives have been synthesized via the reaction of 2-amino-4-oxo-4H-chromene-3-carbonitriles 3(a-f) with different reagents and characterized by IR, H-1 NMR, C-13 NMR, mass spectrometry and elemental analysis. The anti-tubercular and antimicrobial activities of the synthesized compounds were investigated. [GRAPHICS] .
引用
收藏
页码：451 / 462
页数：12
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