The first total synthesis of phebaclavin A and C

被引:2
|
作者
Zhang, Y [1 ]
Liu, D [1 ]
Li, Y [1 ]
Cao, XP [1 ]
机构
[1] Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Organ Chem, Lanzhou 730000, Peoples R China
关键词
phebaclavin A; phebaclavin C; solvent-free cyclizing reaction; Wittig reaction;
D O I
10.1002/cjoc.200591453
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Phebaclavin A (1) and C (2) were synthesized in 60% and 58% total yields over 5 steps from commercially available starting meterials respectively. The synthesis feature was usage of the Wittig reaction twice and solvent-free cyclizing reaction as the key steps.
引用
收藏
页码:1453 / 1456
页数:4
相关论文
共 50 条
  • [1] First total synthesis of (±) Maackin
    Yang, Y
    Bie, PY
    Zhang, CL
    Pan, XF
    JOURNAL OF CHEMICAL RESEARCH, 2003, (05) : 266 - 267
  • [2] First stereoselective total synthesis of (-)-Inohanalactone
    Sharma, Kapil
    Surineni, Naresh
    Gholap, Shivajirao L.
    TETRAHEDRON LETTERS, 2020, 61 (50)
  • [3] First Stereoselective Total Synthesis of Tumonoic Acid A and its Derivatives
    Nagalatha, G.
    Narala, Siva Ganesh
    Narsaiah, A. Venkat
    SYNOPEN, 2018, 2 (03): : 251 - 255
  • [4] First total synthesis and reassignment of absolute configuration of diosniponol A and B
    Yadav, J. S.
    Singh, Vinay K.
    Thirupathaiah, B.
    Reddy, A. Bal
    TETRAHEDRON LETTERS, 2014, 55 (32) : 4427 - 4429
  • [5] Towards the total synthesis of amphidinolide E: an enantioselective synthesis of C12-C29 fragment
    Gurjar, MK
    Mohapatra, S
    Phalgune, UD
    Puranik, VG
    Mohapatra, DK
    TETRAHEDRON LETTERS, 2004, 45 (42) : 7899 - 7902
  • [6] First concise total synthesis of 5-epi-prelactone B
    Srihari, P.
    Ravindar, K.
    Somaiah, R.
    Yadav, J. S.
    SYNTHETIC COMMUNICATIONS, 2008, 38 (09) : 1389 - 1397
  • [8] Total Synthesis of (-)-Cleistenolide
    Babu, Dokuburra Chanti
    Ashalatha, Kankati
    Rao, Chitturi Bhujanga
    Jondoss, Jon Paul Selvam
    Venkateswarlu, Yenamandra
    HELVETICA CHIMICA ACTA, 2011, 94 (12) : 2215 - 2220
  • [9] Total Synthesis of Okaspirodiol
    Madasu, Madhu
    Mohapatra, Debendra K.
    CHEMISTRYSELECT, 2023, 8 (13):
  • [10] Total synthesis of gigantetrocin A
    Wang, ZM
    Tian, SK
    Shi, M
    CHIRALITY, 2000, 12 (07) : 581 - 589