The infrared fingerprint signals of silica nanoparticles and its application in immunoassay

被引：25
作者：
Ding, Yadan [1 ]
Chu, Xueying [1 ]
Hong, Xia [1 ]
Zou, Peng [1 ]
Liu, Yichun [1 ]
机构：
[1] NE Normal Univ, Ctr Adv Optoelect Funct Mat Res, Key Lab UV Light Emitting Mat & Technol, Minist Educ, Changchun 130024, Peoples R China
来源：
APPLIED PHYSICS LETTERS | 2012年 / 100卷 / 01期
基金：
中国国家自然科学基金;
关键词：
THIN-FILMS; SPECTROSCOPY; ABSORPTION; SPECTRA;
D O I：
10.1063/1.3673549
中图分类号：
O59 [应用物理学];
学科分类号：
摘要：
Infrared absorption properties of silica nanoparticles were studied. The transverse optical and the longitudinal optical phonon modes from the silica were proved to be the characteristic spectroscopic fingerprint signals. Based on this, a sandwich-structured immunoassay was performed, and the detection of the analyte (human IgG) was achieved by using biofunctional silica nanoparticles as infrared probes. The immunoassay based on Fourier transform infrared reflection absorption spectroscopy of silica nanoparticles shows significant value for potential applications in many areas, such as biomedicine, food safety, and waste treatment. (C) 2012 American Institute of Physics. [doi: 10.1063/1.3673549]
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页数：3
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