Chronic thromboembolic pulmonary Hypertension (CTEPH) 2014 A Position Paper

被引:8
作者
Wilkens, H. [1 ]
Lang, I. [2 ]
Blankenburg, T. [3 ]
Grohe, C. [4 ]
Guth, S. [5 ]
Held, M. [6 ]
Klepetko, W. [8 ]
Konstantinides, S. [7 ]
Kramm, T. [5 ]
Krueger, U. [9 ]
Lankeit, M. [7 ]
Schaefers, H. J. [10 ]
Seyfarth, H. J. [11 ]
Mayer, E. [5 ]
机构
[1] Univ Klinikum Saarlandes, Klin Innere Med 5, D-66421 Homburg, Germany
[2] Med Univ Wien, Abt Kardiol, Klin Innere Med 2, Vienna, Austria
[3] Krankenhaus Martha Maria Halle Dolau, Klin Innere Med 2, Halle, Germany
[4] Evangelische Lungenklin Berlin Buch, Klin Pneumol, Berlin, Germany
[5] Max Planck Inst Physiol & Clin Res, Kerckhoff Klin, Abt Thoraxchirurg, Bad Nauheim, Germany
[6] Missionsarztliche Klin Wurzburg, Wurzburg, Germany
[7] Univ Med Mainz, Ctr Thrombose & Hamostase, Mainz, Germany
[8] Med Univ Wien, Klin Abt Thoraxchirurg, Vienna, Austria
[9] Herzzentrum Duisburg, Klin Kardiol & Angiol, Duisburg, Germany
[10] Univ Klinikum Saarlandes, Klin Thorax Herz Gefasschirurg, Homburg, Germany
[11] Univ Klinikum Leipzig, Abt Pneumol, Dept Innere Med Neurol & Dermatol, Leipzig, Germany
关键词
INTERNATIONAL PROSPECTIVE REGISTRY; LONG-TERM TREATMENT; ARTERIAL-HYPERTENSION; RISK-FACTORS; VENOUS THROMBOEMBOLISM; ENDARTERECTOMY SURGERY; CIRCULATORY ARREST; INHALED ILOPROST; ANGIOPLASTY; DIAGNOSIS;
D O I
10.1055/s-0034-1370220
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This position paper summarises current developments in chronic thromboembolic pulmonary hypertension (CTEPH) including diagnostic approaches and treatment options. Based on the guidelines of the task force of CTEPH experts at the 5th World Symposium on Pulmonary Hypertension in Nice 2013. Open questions arising during the treatment of patients with CTEPH are addressed. Patients with suspected CTEPH should undergo echocardiography and cardiopulmonary exercise testing. A ventilation/perfusion scan is the recommended imaging test for screening in the diagnostic algorithm for the evaluation of CTEPH. CTEPH-patients should be discussed in an expert center with an interdisciplinary team and an experienced PEA surgeon to decide the further treatment. Pulmonary endarterectomy (PEA) is the treatment of choice for patients with CTEPH. Medical therapy with PH-targeted medications for inoperable CTEPH and residual disease after PEA should only be initiated if evaluation reveals that the patient is no candidate for a PEA. Current data suggest that CTEPH patients treated with PEA have a better long-term survival rate and quality of life than patients treated with medical therapy. ©Georg Thieme Verlag KG Stuttgart New York.
引用
收藏
页码:S155 / S165
页数:11
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