The dynamics of spiral tip adjacent to inhomogeneity in cardiac tissue

被引：18

作者：

Zhang, Juan ^{[1
]}

Tang, Jun ^{[1
]}

Ma, Jun ^{[2
]}

Luo, Jin Ming ^{[3
]}

Yang, Xian Qing ^{[1
]}

机构：

[1] China Univ Min & Technol, Sch Phys, Xuzhou 221116, Peoples R China

[2] Lanzhou Univ Technol, Dept Phys, Lanzhou 730050, Peoples R China

[3] China Univ Min & Technol, Sch Math, Xuzhou 221116, Peoples R China

来源：

PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS | 2018年 / 491卷

关键词：

Spiral wave; Cardiac tissue; Inhomogeneity; VENTRICULAR-FIBRILLATION; WAVES; MODEL; OBSTACLES; MUSCLE; TACHYCARDIA; TRANSITION; ATTACHMENT; INSIGHTS; SIZE;

D O I：

10.1016/j.physa.2017.09.051

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Rotating spiral waves in cardiac tissue are implicated in life threatening cardiac arrhythmias. Experimental and theoretical evidences suggest the inhomogeneities in cardiac tissue play a significant role in the dynamics of spiral waves. Based on a modified 2D cardiac tissue model, the interaction of inhomogeneity on the nearby rigidly rotating spiral wave is numerically studied. The adjacent area of the inhomogeneity is divided to two areas, when the initial rotating center of the spiral tip is located in the two areas, the spiral tip will be attracted and anchor on the inhomogeneity finally, or be repulsed away. The width of the area is significantly dependent on the intensity and size of the inhomogeneity. Our numerical study sheds some light on the mechanism of the interaction of inhomogeneity on the spiral wave in cardiac tissue. (c) 2017 Elsevier B.V. All rights reserved.

引用

页码：340 / 346

页数：7

共 32 条

[1] Negative filament tension at high excitability in a model of cardiac tissue [J].

Alonso, Sergio ;

Panfilov, Alexander V. .

PHYSICAL REVIEW LETTERS, 2008, 100 (21)

[2] A computationally efficient electrophysiological model of human ventricular cells [J].

Bernus, O ;

Wilders, R ;

Zemlin, CW ;

Verschelde, H ;

Panfilov, AV .

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2002, 282 (06) :H2296-H2308

[3] Orbital Motion of Spiral Waves in Excitable Media [J].

Biktashev, V. N. ;

Barkley, D. ;

Biktasheva, I. V. .

PHYSICAL REVIEW LETTERS, 2010, 104 (05)

[4] Phase-resolved analysis of the susceptibility of pinned spiral waves to far-field pacing in a two-dimensional model of excitable media [J].

Bittihn, Philip ;

Squires, Amgad ;

Luther, Gisa ;

Bodenschatz, Eberhard ;

Krinsky, Valentin ;

Parlitz, Ulrich ;

Luther, Stefan .

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, 2010, 368 (1918) :2221-2236

[5] Electroelastic unpinning of rotating vortices in biological excitable media [J].

Cherubini, C. ;

Filippi, S. ;

Gizzi, A. .

PHYSICAL REVIEW E, 2012, 85 (03)

[6] Electric field perturbations of spiral waves attached to millimeter-size obstacles [J].

Cysyk, Joshua ;

Tung, Leslie .

BIOPHYSICAL JOURNAL, 2008, 94 (04) :1533-1541

[7] Theoretical insights into the mechanism of spiral Ca2+ wave initiation in Xenopus oocytes [J].

Dupont, G .

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 1998, 275 (01) :C317-C322

[8] Dispersion gap and localized spiral waves in a model for intracellular Ca2+ dynamics [J].

Falcke, M ;

Or-Guil, M ;

Bär, M .

PHYSICAL REVIEW LETTERS, 2000, 84 (20) :4753-4756

[9] Complex-periodic spiral waves in confluent cardiac cell cultures induced by localized inhomogeneities [J].

Hwang, SM ;

Kim, TY ;

Lee, KJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (29) :10363-10368

[10]

Ikeda T, 1997, CIRC RES, V81, P753

← 1 2 3 4 →