Mechatronic system for in-bore MRI-guided insertion of needles to the prostate: An in vivo needle guidance accuracy study

被引:13
|
作者
Cepek, Jeremy [1 ,2 ]
Lindner, Uri [1 ]
Ghai, Sangeet [3 ]
Louis, Alyssa S. [1 ]
Davidson, Sean R. H. [4 ]
Gertner, Mark [5 ]
Hlasny, Eugen [3 ]
Sussman, Marshall S. [3 ]
Fenster, Aaron [2 ,6 ]
Trachtenberg, John [1 ]
机构
[1] Univ Hlth Network, Div Urol, Dept Surg Oncol, Toronto, ON, Canada
[2] Univ Western Ontario, Robarts Res Inst, London, ON N6A 5B7, Canada
[3] Univ Hlth Network, Joint Dept Med Imaging, Toronto, ON, Canada
[4] Univ Hlth Network, Ontario Canc Inst, Toronto, ON, Canada
[5] Univ Hlth Network, Ontario Canc Inst, Div Biophys & Bioimaging, Toronto, ON, Canada
[6] Univ Western Ontario, Biomed Engn, London, ON N6A 5B7, Canada
基金
加拿大健康研究院;
关键词
needle guidance; prostate cancer; focal therapy; focal laser ablation therapy; targeted biopsy; FOCAL THERAPY; THERMAL THERAPY; CANCER; BRACHYTHERAPY; BIOPSY; SCANNER;
D O I
10.1002/jmri.24742
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
BackgroundTo present our experiences in initial clinical evaluation of a novel mechatronic system for in-bore guidance of needles to the prostate for MRI-guided prostate interventions in 10 patients. We report accuracy of this device in the context of focal laser ablation therapy for localized prostate cancer. MethodsAn MRI-compatible needle guidance device was developed for transperineal prostate interventions. Ten patients underwent MRI-guided focal laser ablation therapy with device-mediated laser fiber delivery. We recorded needle guidance error and needle delivery time. ResultsA total of 37 needle insertions were evaluated. Median needle guidance error was 3.5 mm (interquartile range, 2.1-5.4 mm), and median needle delivery time was 9 min (interquartile range, 6.5-12 min). ConclusionThis system provides a reliable method of accurately aligning needle guides for in-bore transperineal needle delivery to the prostate. J. Magn. Reson. Imaging 2015;42:48-55. (c) 2014 Wiley Periodicals, Inc.
引用
收藏
页码:48 / 55
页数:8
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