Greatly Enhanced Removal of Volatile Organic Carcinogens by a Genetically Modified Houseplant, Pothos Ivy (Epipremnum aureum) Expressing the Mammalian Cytochrome P450 2e1 Gene

被引:26
作者
Zhang, Long [1 ]
Routsong, Ryan [1 ]
Strand, Stuart E. [1 ]
机构
[1] Univ Washington, Dept Civil & Environm Engn, Box 355014, Seattle, WA 98195 USA
关键词
GREEN FLUORESCENT PROTEIN; FORMALDEHYDE DEHYDROGENASE; AIR-POLLUTANTS; TRANSFORMATION; DETOXIFICATION; METABOLISM; PLANTS; PHYTOREMEDIATION; OVEREXPRESSION; DEGRADATION;
D O I
10.1021/acs.est.8b04811
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The indoor air in urban homes of developed countries is usually contaminated with significant levels of volatile organic carcinogens (VOCs), such as formaldehyde, benzene, and chloroform. There is a need for a practical, sustainable technology for the removal of VOCs in homes. Here we show that a detoxifying transgene, mammalian cytochrome P450 2e1 can be expressed in a houseplant, Epipremnum aureum, pothos ivy, and that the resulting genetically modified plant has sufficient detoxifying activity against benzene and chloroform to suggest that biofilters using transgenic plants could remove VOCs from home air at useful rates.
引用
收藏
页码:325 / 331
页数:7
相关论文
共 34 条
  • [1] Enhanced formaldehyde detoxification by overexpression of glutathione-dependent formaldehyde dehydrogenase from Arabidopsis
    Achkor, H
    Díaz, M
    Fernández, MR
    Biosca, JA
    Parés, X
    Martínez, MC
    [J]. PLANT PHYSIOLOGY, 2003, 132 (04) : 2248 - 2255
  • [2] CHEN H, 1994, BIOTECHNIQUES, V16, P664
  • [3] A versatile vector system for multiple gene expression in plants
    Chung, SM
    Frankman, EL
    Tzfira, T
    [J]. TRENDS IN PLANT SCIENCE, 2005, 10 (08) : 357 - 361
  • [4] ACTIVITY OF A MAIZE UBIQUITIN PROMOTER IN TRANSGENIC RICE
    CORNEJO, MJ
    LUTH, D
    BLANKENSHIP, KM
    ANDERSON, OD
    BLECHL, AE
    [J]. PLANT MOLECULAR BIOLOGY, 1993, 23 (03) : 567 - 581
  • [5] Characterisation of urban inhalation exposures to benzene, formaldehyde and acetaldehyde in the European Union
    de Bruin, Yuri Bruinen
    Koistinen, Kimmo
    Kephalopoulos, Stylianos
    Geiss, Otmar
    Tirendi, Salvatore
    Kotzias, Dimitrios
    [J]. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2008, 15 (05) : 417 - 430
  • [6] Reducing formaldehyde exposure in office environments using plants
    Dingle, P
    Tapsell, P
    Hu, S
    [J]. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 2000, 64 (02) : 302 - 308
  • [7] Enhanced phytoremediation of volatile environmental pollutants with transgenic trees
    Doty, Sharon L.
    James, C. Andrew
    Moore, Allison L.
    Vajzovic, Azra
    Singleton, Glenda L.
    Ma, Caiping
    Khan, Zareen
    Xin, Gang
    Kang, Jun Won
    Park, An Young
    Meilan, Richard
    Strauss, Steven H.
    Wilkerson, Jasmine
    Farin, Federico
    Strand, Stuart E.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (43) : 16816 - 16821
  • [8] Enhanced metabolism of halogenated hydrocarbons in transgenic plants containing mammalian cytochrome P450 2E1
    Doty, SL
    Shang, TQ
    Wilson, AM
    Tangen, J
    Westergreen, AD
    Newman, LA
    Strand, SE
    Gordon, MP
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (12) : 6287 - 6291
  • [9] DETOXIFICATION OF FORMALDEHYDE BY THE SPIDER PLANT (CHLOROPHYTUM-COMOSUM L) AND BY SOYBEAN (GLYCINE-MAX L) CELL-SUSPENSION CULTURES
    GIESE, M
    BAUERDORANTH, U
    LANGEBARTELS, C
    SANDERMANN, H
    [J]. PLANT PHYSIOLOGY, 1994, 104 (04) : 1301 - 1309
  • [10] AN ASSESSMENT OF BOTANICAL AIR PURIFICATION AS A FORMALDEHYDE MITIGATION MEASURE UNDER DYNAMIC LABORATORY CHAMBER CONDITIONS
    GODISH, T
    GUINDON, C
    [J]. ENVIRONMENTAL POLLUTION, 1989, 62 (01) : 13 - 20