Hypoglycemia Unawareness in Insulinoma Revealed with Flash Glucose Monitoring Systems

被引：14
作者：
Sugawa, Taku [1 ]
Murakami, Takaaki [1 ]
Yabe, Daisuke [1 ]
Kashima, Riko [1 ]
Tatsumi, Makiko [1 ]
Ooshima, Shinobu [1 ]
Joo, Erina [1 ]
Wada, Keiko [1 ]
Yoshizawa, Atsushi [2 ]
Masui, Toshihiko [2 ]
Nakamoto, Yuji [3 ]
Yamauchi, Yuki [4 ]
Kodame, Yuzo [4 ]
Iemure, Yoshiki [5 ]
Ogura, Masahito [1 ]
Yasoda, Akihiro [1 ]
Inagaki, Nobuya [1 ]
机构：
[1] Kyoto Univ, Dept Diabet Endocrinol & Nutr, Grad Sch Med, Kyoto, Japan
[2] Kyoto Univ, Dept Hepatobiliary Pancreat Surg & Transplantat, Grad Sch Med, Kyoto, Japan
[3] Kyoto Univ, Dept Diagnost Imaging & Nucl Med, Grad Sch Med, Kyoto, Japan
[4] Kyoto Univ, Grad Sch Med, Dept Gastroenterol & Hepatol, Kyoto, Japan
[5] Kyoto Univ, Dept Diagnost Pathol, Grad Sch Med, Kyoto, Japan
来源：
INTERNAL MEDICINE | 2018年 / 57卷 / 23期
基金：
日本学术振兴会;
关键词：
insulinoma; flash glucose monitoring; continuous glucose monitoring; hypoglycemia; DOTATOC; hypoglycemia unawareness; DIAGNOSIS; PET/CT;
D O I：
10.2169/internalmedicine.1173-18
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The delayed diagnosis of insulinoma remains a clinical issue. One of the main causes of such a delay is hypoglycemia unawareness. A 53-year-old woman fell unconscious during postprandial exercises. Flash glucose monitoring (FGM) systems revealed glucose profiles with fasting hypoglycemia, which facilitated the clinical diagnosis of insulinoma even though she was unaware of her hypoglycemia. The preoperative comparison of the blood glucose values provided by FGM with those obtained from capillary blood were consistent. Thus, FGM may have potential utility in revealing the presence of insulinoma-induced hypoglycemia.
引用
收藏
页码：3407 / 3412
页数：6
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