What Is the Heart? Anatomy, Function, Pathophysiology, and Misconceptions

被引:40
作者
Buckberg, Gerald D. [1 ]
Nanda, Navin C. [2 ]
Nguyen, Christopher [3 ]
Kocica, Mladen J. [4 ]
机构
[1] UCLA, Dept Cardiothorac Surg, David Geffen Sch Med, 10833 Le Conte Ave,Room 62-258 CHS,POB 951741, Los Angeles, CA 90095 USA
[2] Univ Alabama Birmingham, Div Cardiovasc Dis, 1900 Univ Blvd, Birmingham, AL 35233 USA
[3] Cedars Sinai Med Ctr, 8700 Beverly Blvd PACT,Suite 800, Los Angeles, CA 90048 USA
[4] UC Clin Ctr Serbia, Clin Cardiac Surg, 8th Kosta Todorovic St, Belgrade 11000, Serbia
关键词
conventional heart anatomy; helical ventricular myocardial band; mitral valve opening; isovolumic relaxation time; RV function; diastolic dysfunction; LEFT-VENTRICULAR TWIST; CARDIAC-RESYNCHRONIZATION THERAPY; MAGNETIC-RESONANCE; DIASTOLIC DYSFUNCTION; EJECTION FRACTION; MYOCARDIAL MOTION; MITRAL-VALVE; LONG-TERM; MUSCULAR ARCHITECTURE; FIBER ORIENTATION;
D O I
10.3390/jcdd5020033
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cardiac dynamics are traditionally linked to a left ventricle, right ventricle, and septum morphology, a topography that differs from the heart's five-century-old anatomic description of containing a helix and circumferential wrap architectural configuration. Torrent Guasp's helical ventricular myocardial band (HVMB) defines this anatomy and its structure, and explains why the heart's six dynamic actions of narrowing, shortening, lengthening, widening, twisting, and uncoiling happen. The described structural findings will raise questions about deductions guiding "accepted cardiac mechanics", and their functional aspects will challenge and overturn them. These suppositions include the LV, RV, and septum description, timing of mitral valve opening, isovolumic relaxation period, reasons for torsion/twisting, untwisting, reasons for longitudinal and circumferential strain, echocardiographic sub segmentation, resynchronization, RV function dynamics, diastolic dysfunction's cause, and unrecognized septum impairment. Torrent Guasp's revolutionary contributions may alter future understanding of the diagnosis and treatment of cardiac disease.
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页数:29
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