Advances in cancer therapy through the use of carbon nanotube-mediated targeted hyperthermia

被引:71
作者
Iancu, Cornel [1 ]
Mocan, Lucian [1 ]
机构
[1] Iuliu Hatieganu Univ Med & Pharm, Dept Nanomed, Surg Clin 3, Cluj Napoca, Romania
来源
INTERNATIONAL JOURNAL OF NANOMEDICINE | 2011年 / 6卷
关键词
carbon nanotubes; cancer targeting; functionalization; optical excitation; cancer treatment; ENHANCED TUMOR UPTAKE; IN-VITRO; SERUM-ALBUMIN; THERMAL ABLATION; MONOCLONAL-ANTIBODY; PANCREATIC-CANCER; DRUG-DELIVERY; BREAST-CANCER; CELLS; FUNCTIONALIZATION;
D O I
10.2147/IJN.S23588
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Carbon nanotubes (CNTs) are emerging versatile tools in nanomedicine applications, particularly in the field of cancer targeting. Due to diverse surface chemistry and unique thermal properties, CNTs can act as strong optical absorbers in near infrared light where biological systems prove to be highly transparent. The process of laser-mediated ablation of cancer cells marked with biofunctionalized CNTs is frequently termed "nanophotothermolysis." This paper illustrates the potential of engineered CNTs as laser-activated photothermal agents for the selective nanophotothermolysis of cancer cells.
引用
收藏
页码:1675 / 1684
页数:10
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