A case of human infection with avian Influenza A/H7N9 virus in Beijing: virological and serological analysis

被引：1

作者：

Pan, Yang ^{[1
]}

Shi, Weixian ^{[1
]}

Yang, Peng ^{[1
]}

Wu, Shuangsheng ^{[1
]}

Peng, Xiaomin ^{[1
]}

Cui, Shujian ^{[1
]}

Zhang, Daitao ^{[1
]}

Lu, Guilan ^{[1
]}

Zhao, Jiachen ^{[1
]}

Liu, Yimeng ^{[1
]}

Wang, Quanyi ^{[1
]}

机构：

[1] Beijing Ctr Dis Prevent & Control CDC, Inst Infect Dis & Endem Dis Control, Beijing, Peoples R China

来源：

JOURNAL OF INFECTION IN DEVELOPING COUNTRIES | 2015年 / 9卷 / 03期

关键词：

Influenza; H7N9 avian influenza; drug resistance; antibody; viral load; A H7N9 VIRUS; A(H7N9) VIRUS;

D O I：

10.3855/jidc.5875

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

This study described some essential viral and sera-characteristics of A/H7N9 virus infection in a 61-year old case patient. With the antiviral therapy and respiratory support, the patient showed a significant decrease of viral loads from 6.72 log(10) copies/mL to 0 in 22 days, and a correlated increase of serum hemagglutination inhibition titers during the same period. Phylogenetic analysis demonstrated that the isolated strain was highly homologous to previous strains isolated in the southeast of China. Drug resistance-associated R292K mutation became detectable 17 days after antiviral therapy, but no remarkable influence on the viral clearance was observed.

引用

页码：317 / 320

页数：4

共 50 条

[21] Avian Influenza A(H7N9) Virus Infection in 2 Travelers Returning from China to Canada, January 2015
Skowronski, Danuta M.
Chambers, Catharine
Gustafson, Reka
Purych, Dale B.
Tang, Patrick
Bastien, Nathalie
Krajden, Mel
Li, Yan
EMERGING INFECTIOUS DISEASES, 2016, 22 (01) : 71 - 74
[22] Immune derangement occurs in patients with H7N9 avian influenza
Wei Wu
Yu Shi
Hainv Gao
Weifeng Liang
Jifang Sheng
Lanjuan Li
Critical Care, 18
[23] Recombinant virus-like particles elicit protective immunity against avian influenza A(H7N9) virus infection in ferrets
Liu, Ye V.
Massare, Michael J.
Pearce, Melissa B.
Sun, Xiangjie
Belser, Jessica A.
Maines, Taronna R.
Creager, Hannah M.
Glenn, Gregory M.
Pushko, Peter
Smith, Gale E.
Tumpey, Terrence M.
VACCINE, 2015, 33 (18) : 2152 - 2158
[24] The Dynamics of the Ferret Immune Response During H7N9 Influenza Virus Infection
Horman, William S. J.
Nguyen, Thi H. O.
Kedzierska, Katherine
Butler, Jeffrey
Shan, Songhua
Layton, Rachel
Bingham, John
Payne, Jean
Bean, Andrew G. D.
Layton, Daniel S.
FRONTIERS IN IMMUNOLOGY, 2020, 11
[25] Clinical variability in onset of influenza A (H7N9) infection
Wang Shu-ying
Ren Shu-hua
Huang Mei-xian
Yu Dao-jun
Shen Qiang
Zhao Hong-feng
Lu Qiao-hong
Qian Shen-xian
CHINESE MEDICAL JOURNAL, 2013, 126 (21) : 4194 - 4196
[26] Sex differences in H7N9 influenza A virus pathogenesis
Hoffmann, Julia
Otte, Anna
Thiele, Swantje
Lotter, Hannelore
Shu, Yuelong
Gabriel, Guelsah
VACCINE, 2015, 33 (49) : 6949 - 6954
[27] Serologic assay for avian-origin influenza A (H7N9) virus in adults of Shanghai, Guangzhou and Yunnan, China
Wang, Wenbo
Peng, Haoran
Tao, Qingyuan
Zhao, Xuetao
Tang, Hailin
Tang, Ziwei
Wang, Yan
Wang, Yue
Zhao, Ping
Qi, Zhongtian
JOURNAL OF CLINICAL VIROLOGY, 2014, 60 (03) : 305 - 308
[28] Willingness to accept a future influenza A(H7N9) vaccine in Beijing, China
Wu, Shuangsheng
Su, Jianting
Yang, Peng
Zhang, Haiyan
Li, Hongjun
Chu, Yanhui
Hua, Weiyu
Li, Chao
Tang, Yaqing
Wang, Quanyi
VACCINE, 2018, 36 (04) : 491 - 497
[29] H7N3 live attenuated influenza vaccine has a potential to protect against new H7N9 avian influenza virus
Rudenko, Larisa
Isakova-Sivak, Irina
Donina, Svetlana
VACCINE, 2013, 31 (42) : 4702 - 4705
[30] Epidemiologic report and serologic findings for household contacts of three cases of influenza A (H7N9) virus infection
Qiu, Chao
Yuan, Songhua
Di Tian
Yang, Yu
Zhang, Anli
Chen, Qingguo
Wan, Yanmin
Song, Zhigang
He, Jing
Li, Liangzhu
Sun, Jun
Zhou, Mingzhe
Qiu, Chenli
Zhang, Zhiyong
Lu, Shuihua
Zhang, Xiaoyan
Hu, Yunwen
Xu, Jianqing
JOURNAL OF CLINICAL VIROLOGY, 2014, 59 (02) : 129 - 131

← 1 2 3 4 5 →