Drug-Induced Liver Disease

被引：58
|
作者：
Davern, Timothy J. [1 ]
机构：
[1] Calif Pacific Med Ctr, Dept Transplantat, San Francisco, CA 94115 USA
来源：
CLINICS IN LIVER DISEASE | 2012年 / 16卷 / 02期
关键词：
Hepatotoxicity; Liver injury; Hepatotoxins; Hepatitis E virus; HEPATITIS-E VIRUS; CAUSALITY ASSESSMENT METHOD; UNITED-STATES; ACETAMINOPHEN HEPATOTOXICITY; CLINICAL-FEATURES; HYS LAW; INJURY; FAILURE; INFECTION; EPIDEMIOLOGY;
D O I：
10.1016/j.cld.2012.03.002
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Drug-induced liver injury (DILI), also known as hepatotoxicity, refers to liver injury caused by drugs or other chemical agents, and represents a special type of adverse drug reaction. It has been estimated that more than 600 drugs and chemicals have been associated with significant liver injury. Many previous reviews have focused on DILI pathogenesis or have outlined the clinical features of liver injury linked to different drugs. This article briefly touches on several areas that are potentially vexing for both the novice and cognoscenti, with the goal of guiding the consultant through one of the most challenging areas of hepatology.
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页码：231 / +
页数：16
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