Recent advances in curdlan biosynthesis, biotechnological production, and applications

被引：109

作者：

Zhan, Xiao-Bei ^{[1
,2
]}

Lin, Chi-Chung ^{[1
,2
]}

Zhang, Hong-Tao ^{[1
,2
]}

机构：

[1] Jiangnan Univ, Sch Biotechnol, Minist Educ, Key Lab Ind Biotechnol, Wuxi 214122, Peoples R China

[2] Jiangnan Univ, Sch Biotechnol, Minist Educ, Key Lab Carbohydrate Chem & Biotechnol, Wuxi 214122, Peoples R China

来源：

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | 2012年 / 93卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Curdlan; Oligosaccharides; Biosynthesis; Production improvement; New applications; BETA-GLUCAN RECEPTOR; FAECALIS VAR MYXOGENES; SP ATCC 31749; AGROBACTERIUM SP; DECTIN-1; INNATE; RECOGNITION; MUTANT; ACTIVATION; SULFATE;

D O I：

10.1007/s00253-011-3740-2

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Curdlan is a water-insoluble beta-(1,3)-glucan produced by Agrobacterium species under nitrogen-limited condition. Its heat-induced gelling properties render curdlan to be very useful in the food industry initially. Recent advances in the understanding of the role curdlan plays in both innate and adaptive immunity lead to its growing applications in biomedicine. Our review focuses on the recent advances on curdlan biosynthesis and the improvements of curdlan fermentation production both from our laboratory and many others as well as the latest advances on the new applications of curdlan and its derivatives particularly in their immunological functions in biomedicine.

引用

页码：525 / 531

页数：7

共 49 条

[11] MECHANISM OF THE INHIBITORY EFFECT OF CURDLAN SULFATE ON HIV-1 INFECTION IN-VITRO [J].