Molecular imaging of cancer: MR spectroscopy and beyond

被引：50
作者：
Pinker, K. [1 ]
Stadlbauer, A. [3 ]
Bogner, W. [2 ]
Gruber, S. [2 ]
Helbich, T. H. [1 ,2 ]
机构：
[1] Med Univ Vienna, Dept Radiol, Div Mol & Gender Imaging, A-1090 Vienna, Austria
[2] Med Univ Vienna, Dept Radiol, MR Ctr Excellence, A-1090 Vienna, Austria
[3] Univ Erlangen Nurnberg, Dept Neurosurg, Neuroctr, Erlangen, Germany
来源：
EUROPEAN JOURNAL OF RADIOLOGY | 2012年 / 81卷 / 03期
关键词：
Molecular imaging; MR spectroscopy; Cancer; Sodium imaging; Diffusion-weighted imaging; Breast; Prostate; Brain; MAGNETIC-RESONANCE-SPECTROSCOPY; HUMAN BRAIN-TUMORS; INVASIVE CERVICAL-CANCER; HUMAN BREAST-LESIONS; TISSUE SODIUM CONCENTRATION; PROTON NMR-SPECTROSCOPY; SQUAMOUS-CELL CARCINOMA; DIFFUSION-WEIGHTED MRI; LOW-GRADE GLIOMAS; IN-VIVO;
D O I：
10.1016/j.ejrad.2010.04.028
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Proton magnetic resonance spectroscopic imaging is a non-invasive diagnostic tool for the investigation of cancer metabolism. As an adjunct to morphologic and dynamic magnetic resonance imaging, it is routinely used for the staging, assessment of treatment response, and therapy monitoring in brain, breast, and prostate cancer. Recently, its application was extended to other cancerous diseases, such as malignant soft-tissue tumours, gastrointestinal and gynecological cancers, as well as nodal metastasis. In this review, we discuss the current and evolving clinical applications of proton magnetic resonance spectroscopic imaging. In addition, we will briefly discuss other evolving techniques, such as phosphorus magnetic resonance spectroscopic imaging, sodium imaging and diffusion-weighted imaging in cancer assessment. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：566 / 577
页数：12
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