AIE-active iridium(III) complex integrated with upconversion nanoparticles for NIR-irradiated photodynamic therapy

被引：30

作者：

Liu, Shengnan ^{[1
]}

Han, Jiahong ^{[1
]}

Chang, Yulei ^{[2
]}

Wang, Weijin ^{[1
]}

Wang, Runlin ^{[1
]}

Wang, Ziwei ^{[1
]}

Li, Guangzhe ^{[3
]}

Zhu, Dongxia ^{[1
]}

Bryce, Martin R. ^{[4
]}

机构：

[1] Northeast Normal Univ, Dept Chem, Key Lab Nanobiosensing & Nanobioanal Univ Jilin P, 5268 Renmin St, Changchun 130024, Jilin, Peoples R China

[2] Chinese Acad Sci, Changchun Inst Opt Fine Mech & Phys, State Key Lab Luminescence & Applicat, Changchun 130033, Jilin, Peoples R China

[3] Changchun Univ Chinese Med, Jilin Prov Sci & Technol Innovat Ctr Hlth Food Ch, Changchun 130117, Jilin, Peoples R China

[4] Univ Durham, Dept Chem, Durham DH1 3LE, England

来源：

CHEMICAL COMMUNICATIONS | 2022年 / 58卷 / 72期

基金：

英国工程与自然科学研究理事会;

关键词：

AGGREGATION-INDUCED EMISSION;

D O I：

10.1039/d2cc03622c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The integration of an aggregation induced emission (AIE)-active Ir(III) complex and upconversion nanoparticles (UCNPs) has achieved a NIR-irradiated photosensitizer (PS), UCNPs@Ir-2-N. This PS has satisfactory biocompatibility, excellent phototoxicity, good accumulation in cells and high O-1(2) generation ability, thereby effectively killing 4T1 mouse cancer cells in vitro. This work has potential for future photodynamic therapy (PDT) applications.

引用

页码：10056 / 10059

页数：4

共 34 条

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