Synthetic metabolism without the TCA cycle

被引：5

作者：

Lindner, Steffen N. ^{[1
]}

Ralser, Markus ^{[1
]}

机构：

[1] Charite, Dept Biochem, Berlin, Germany

来源：

NATURE METABOLISM | 2022年 / 4卷 / 11期

关键词：

BIOFUELS;

D O I：

10.1038/s42255-022-00668-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The core metabolic pathways are tightly intertwined, creating challenges for metabolic engineering. Yu et al. present a synthetic decarboxylation cycle that substitutes the TCA cycle in energy metabolism, gaining high yields in the production of reduced compounds such as fatty acids.

引用

页码：1438 / 1439

页数：2

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