The prevalence of genuine empty follicle syndrome

被引：37

作者：

Mesen, Tolga B. ^{[1
,2
]}

Yu, Bo ^{[1
]}

Richter, Kevin S. ^{[3
]}

Widra, Eric ^{[3
]}

DeCherney, Alan H. ^{[1
]}

Segars, James H. ^{[1
]}

机构：

[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Program Reprod & Adult Endocrinol, Bethesda, MD USA

[2] Carolinas Med Ctr, Dept Obstet & Gynecol, Charlotte, NC 28203 USA

[3] Shady Grove Fertil Reprod Sci Ctr, Rockville, MD USA

来源：

FERTILITY AND STERILITY | 2011年 / 96卷 / 06期

基金：

美国国家卫生研究院;

关键词：

Empty follicle syndrome; oocyte maturation failure; follicle maturation; assisted reproduction; oocyte development; follicle development; hCG resistance; oocyte apoptosis; GROWTH-FACTOR; CONTROVERSIAL SYNDROME; OOCYTE RETRIEVAL; CYCLES; FERTILIZATION; ASPIRATION; MEDIATORS; PATIENT;

D O I：

10.1016/j.fertnstert.2011.09.047

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: To describe the prevalence of "genuine" empty follicle syndrome (EFS) and "false" EFS at assisted reproductive technology (ART). Design: Retrospective cohort. Setting: Large private fertility center. Patient(s): A total of 12,359 patients who underwent ART between 2004 and 2009. Intervention(s): None. Main Outcome Measure(s): The failure to recover an oocyte during oocyte retrieval at ART, with and without a detectable serum beta-hCG on the day of retrieval. Result(s): Two cases of genuine EFS and nine cases of false EFS were identified in the cohort examined. The prevalence of genuine EFS was 0.016%, and the prevalence of false EFS was 0.072%. Only two out of 11 cases of EFS were considered genuine. Conclusion(s): Genuine EFS is a rare occurrence. Because this syndrome tends to recur with dismal pregnancy rates at ART, continued identification and further investigation of the syndrome are needed. (Fertil Steril (R) 2011; 96: 1375-7. (C) 2011 by American Society for Reproductive Medicine.)

引用

页码：1375 / 1377

页数：3

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