Stem cells for the treatment of neurodegenerative diseases

被引：72

作者：

Dantuma, Elise ^{[1
]}

Merchant, Stephanie ^{[1
]}

Sugaya, Kiminobu ^{[1
]}

机构：

[1] Univ Cent Florida, Coll Med, Burnett Sch Biomed Sci, Orlando, FL 32827 USA

来源：

STEM CELL RESEARCH & THERAPY | 2010年 / 1卷

关键词：

AMYOTROPHIC-LATERAL-SCLEROSIS; PARKINSONS-DISEASE; ALZHEIMERS-DISEASE; MULTIPLE-SCLEROSIS; ANIMAL-MODEL; NEUROLOGICAL DISORDERS; EXERTS NEUROPROTECTION; REGENERATIVE MEDICINE; CANCER-THERAPIES; SPLEEN COLONIES;

D O I：

10.1186/scrt37

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Stem cells off er an enormous pool of resources for the understanding of the human body. One proposed use of stem cells has been as an autologous therapy. The use of stem cells for neurodegenerative diseases has become of interest. Clinical applications of stem cells for Alzheimer disease, Parkinson disease, amyotrophic lateral sclerosis, and multiple sclerosis will increase in the coming years, and although great care will need to be taken when moving forward with prospective treatments, the application of stem cells is highly promising.

引用

页数：7

共 74 条

[1] Neuroprotective Effect of Transplanted Human Embryonic Stem Cell-Derived Neural Precursors in an Animal Model of Multiple Sclerosis [J].

Aharonowiz, Michal ;

Einstein, Ofira ;

Fainstein, Nina ;

Lassmann, Hans ;

Reubinoff, Benjamin ;

Ben-Hur, Tamir .

PLOS ONE, 2008, 3 (09)

[2]

[Anonymous], 2010, Alzheimer's Dementia, V6, P158, DOI DOI 10.1016/J.JALZ.2010.01.009

[3] Autologous mesenchymal stem cell transplantation in stroke patients [J].

Bang, OY ;

Lee, JS ;

Lee, PH ;

Lee, G .

ANNALS OF NEUROLOGY, 2005, 57 (06) :874-882

[4] CYTOLOGICAL DEMONSTRATION OF CLONAL NATURE OF SPLEEN COLONIES DERIVED FROM TRANSPLANTED MOUSE MARROW CELLS [J].

BECKER, AJ ;

TILL, JE ;

MCCULLOCH, EA .

NATURE, 1963, 197 (486) :452-&

[5] Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease [J].

Blurton-Jones, Mathew ;

Kitazawa, Masashi ;

Martinez-Coria, Hilda ;

Castello, Nicholas A. ;

Mueller, Franz-Josef ;

Loring, Jeanne F. ;

Yamasaki, Tritia R. ;

Poon, Wayne W. ;

Green, Kim N. ;

LaFerla, Frank M. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (32) :13594-13599

[6] Adult Stem Cell Therapies for Neurological Disorders: Benefits Beyond Neuronal Replacement? [J].

Boucherie, Cedric ;

Hermans, Emmanuel .

JOURNAL OF NEUROSCIENCE RESEARCH, 2009, 87 (07) :1509-1521

[7]

Burt RK, 2009, LANCET NEUROL, V8, P244, DOI 10.1016/S1474-4422(09)70017-1

[8] Dopaminergic Neurons Derived from Human Induced Pluripotent Stem Cells Survive and Integrate into 6-OHDA-Lesioned Rats [J].

Cai, Jingli ;

Yang, Ming ;

Poremsky, Elizabeth ;

Kidd, Sarah ;

Schneider, Jay S. ;

Iacovitti, Lorraine .

STEM CELLS AND DEVELOPMENT, 2010, 19 (07) :1017-1023

[9] Motor neuron degeneration promotes neural progenitor cell proliferation, migration, and neurogenesis in the spinal cords of amyotrophic lateral sclerosis mice [J].

Chi, LY ;

Ke, Y ;

Luo, C ;

Li, BL ;

Gozal, D ;

Kalyanaraman, B ;

Liu, R .

STEM CELLS, 2006, 24 (01) :34-43

[10] Brain-derived neurotrophic factor is reduced in Alzheimer's disease [J].

Connor, B ;

Young, D ;

Yan, Q ;

Faull, RLM ;

Synek, B ;

Dragunow, M .

MOLECULAR BRAIN RESEARCH, 1997, 49 (1-2) :71-81

← 1 2 3 4 5 6 7 8 →