Challenges of implementing fibromyalgia treatment guidelines in current clinical practice

被引:50
作者
Arnold, Lesley M. [1 ]
Clauw, Daniel J. [2 ,3 ,4 ,5 ]
机构
[1] Univ Cincinnati, Coll Med, Womens Hlth Res Program, Dept Psychiat & Behav Neurosci, Cincinnati, OH 45219 USA
[2] Univ Michigan, Dept Anesthesiol, Ann Arbor, MI 48109 USA
[3] Univ Michigan, Dept Med Rheumatol, Ann Arbor, MI 48109 USA
[4] Univ Michigan, Dept Psychiat, Ann Arbor, MI 48109 USA
[5] Univ Michigan, Chron Pain & Fatigue Res Ctr, Ann Arbor, MI 48109 USA
关键词
Fibromyalgia; treatment guidelines; clinical practice; pharmacotherapy; pain management; RANDOMIZED CONTROLLED-TRIAL; COGNITIVE-BEHAVIORAL THERAPY; MAJOR DEPRESSIVE DISORDER; PLACEBO-CONTROLLED TRIAL; DOUBLE-BLIND; TREATMENT PATTERNS; PRIMARY-CARE; DULOXETINE; PREGABALIN; MANAGEMENT;
D O I
10.1080/00325481.2017.1336417
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The current diagnostic and treatment pathway for patients with fibromyalgia (FM) is lengthy, complex, and characterized by multiple physician visits with an average 2-year wait until diagnosis. It is clear that effective identification and appropriate treatment of FM remain a challenge in current clinical practice. Ideally, FM management involves a multidisciplinary approach with the preferable patient pathway originating in primary care but supported by a range of health care providers, including referral to specialist care when necessary. After the publication of individual clinical studies, high-quality reviews, and meta-analyses, recently published FM treatment guidelines have transitioned from an expert consensus to an evidence-based approach. Evidence-based guidelines provide a framework for ensuring early diagnosis and timely adoption of appropriate treatment. However, for successful outcomes, FM treatments must adopt a more holistic approach, which addresses more than just pain. Impact on the associated symptoms of fatigue and cognitive problems, sleep and mood disturbances, and lowered functional status are also important in judging the success of FM therapy. Recently published guidelines recommend the adoption of a symptom-based approach to guide pharmacologic treatment. Emerging treatment options for FM may be best differentiated on the basis of their effect on comorbid symptoms that are often associated with pain (e.g. sleep disturbance, mood, fatigue). The current review discusses the most recently published Canadian guidelines and the implications of the recent European League Against Rheumatism (EULAR) recommendations, with a focus on the challenges of implementing these guidelines in current clinical practice.
引用
收藏
页码:709 / 714
页数:6
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