Patients, Here Comes More Nanotechnology

被引：43

作者：

Chan, Warren C. W. ^{[1
]}

Udugama, Buddhisha ^{[1
]}

Kadhiresan, Pranav ^{[1
]}

Kim, Jisung ^{[1
]}

Mubareka, Samira ^{[2
]}

Weiss, Paul S. ^{[3
,4
,5
]}

Park, Wolfgang J. ^{[6
,7
]}

机构：

[1] Univ Toronto, Inst Biomat & Biomed Engn, Donnelly Ctr Biomol Res, Dept Chem,Dept Chem Engn,Dept Mat Sci & Engn, 164 Coll St, Toronto, ON M5T 2R5, Canada

[2] Sunnybrook Hlth Sci Ctr, 2075 Bayview Ave, Toronto, ON M4N 3M5, Canada

[3] Univ Calif Los Angeles, Calif NanoSyst Inst, Los Angeles, CA 90095 USA

[4] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA

[5] Univ Calif Los Angeles, Dept Mat Sci & Engn, Los Angeles, CA 90095 USA

[6] Univ Marburg, Fachbereich Phys, D-35032 Marburg, Germany

[7] CIC BiomaGUNE, Donostia San Sebastian 20009, Spain

来源：

ACS NANO | 2016年 / 10卷 / 09期

基金：

加拿大自然科学与工程研究理事会;

关键词：

SENSITIVITY; DIAGNOSTICS;

D O I：

10.1021/acsnano.6b05610

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We describe the current difference in reporting the performance of nanotechnology diagnostic devices between technologists and clinicians. This perspective specifies the "metrics" used to evaluate these devices and describes strategies to bridge the gap between these two communities in order to accelerate the translation from academic bench to the clinic. We use two recently published ACS Nano articles to highlight the evaluation of silicon nanowire and surface-enhanced Raman spectroscopy-breath diagnostic tests for patients afflicted with cancer and asthma. These studies represent some of the earliest studies of emerging nanotechnology devices utilizing clinical parameters to assess performance.

引用

页码：8139 / 8142

页数：4

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