Emerging and neglected tropical diseases: translational application of proteomics

被引:3
作者
Denman, Britta [1 ,4 ]
Goodman, Steven R. [2 ,3 ,4 ]
机构
[1] SUNY Hlth Sci Ctr, Dept Med, Syracuse, NY 13210 USA
[2] SUNY Hlth Sci Ctr, Dept Biochem & Mol Biol, Syracuse, NY 13210 USA
[3] SUNY Hlth Sci Ctr, Dept Pediat, Syracuse, NY 13210 USA
[4] SUNY Upstate Med Univ, Syracuse, NY 13210 USA
关键词
proteomics; infectious disease; emerging diseases; vaccine development; pathogen discovery; outbreaks; bioterrorism; biodefense; ANTIBACTERIAL VACCINE DESIGN; BIOMARKER DISCOVERY; HEPATITIS-E; STRUCTURAL PROTEOMICS; VIRAL-HEPATITIS; GENOMICS; VIRUS; LEPTOSPIRA; IDENTIFICATION; FINGERPRINTS;
D O I
10.1258/ebm.2011.011067
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The challenges of identifying and controlling emerging diseases impact individual health, as well as political, social and economic situations. In this review we discuss the role of proteomics for investigation of pathogen discovery, outbreak investigation, bio-defense, disease control, host-pathogen dynamics and vaccine development of emerging and neglected tropical diseases (NTDs). In the future the discipline of proteomics may help define multiple aspects of emerging and NTDs with respect to personalized medicine and public health.
引用
收藏
页码:972 / 976
页数:5
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