FORMULATION AND IN-VITRO EVALUATION OF CONTROLLED RELEASE MATRIX TABLETS OF LORNOXICAM

被引：0
|
作者：
Kumar, P. Suresh [1 ]
Sravani, A. [1 ]
机构：
[1] Browns Coll Pharm, Dept Pharmaceut, Khammam 507305, Telangana, India
来源：
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH | 2020年 / 11卷 / 06期
关键词：
Lornoxicam; Guar gum; Xanthan gum; Carbopol; 934; Controlled release tablets; DRUG-DELIVERY;
D O I：
10.13040/IJPSR.0975-8232.11(6).2793-00
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The aim of the present study was to develop a controlled release formulation of Lornoxicam to maintain constant therapeutic levels of the drug for over 12 h. Guar gum, xantham gum, and carbopol 934 were employed as polymers. All the formulations were passed various physicochemical evaluation parameters, and they were found to be within limits. From the dissolution studies, it was evident that the formulation (F2) showed better and desired drug release patterns, i.e., 99.65% in 12 h. It contains the guar gum polymer. It followed the Higuchi order release kinetics mechanism.
引用
收藏
页码：2793 / 2800
页数：8
相关论文
共 50 条
  • [41] FORMULATION DESIGN AND IN-VITRO EVALUATION OF ZOLMITRIPTAN GASTRORETENSIVE FLOATING MATRIX TABLETS FOR MANAGEMENT OF MIGRAINE
    Zafar, Rana
    Panda, Niranjan
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2015, 6 (09): : 3901 - 3912
  • [42] FORMULATION AND EVALUATION OF SUSTAINED RELEASE MATRIX TABLETS OF BACLOFEN
    Shankar, K. Ravi
    Madhan, K.
    Swetha, G.
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2018, 9 (10): : 4402 - 4409
  • [43] Formulation and Evaluation of Extended Release Carbamazepine Matrix Tablets
    Manivannan, R.
    Balasubramaniam, A.
    Sandeep, G.
    Afsal, V. T. Ibrahim
    ASIAN JOURNAL OF CHEMISTRY, 2009, 21 (06) : 4737 - 4743
  • [44] Sustained Release Coprecipitates and Matrix Tablets of Ibuprofen with Polyacrylic Resin Ⅱ:Formulation and in vitro Evaluation
    马吉德
    朱家璧
    中国药科大学学报, 1998, (04) : 27 - 34
  • [45] CONTROLLED RELEASE FORMULATION DEVELOPMENT AND EVALUATION OF FELODIPINE MATRIX TABLETS BY USING HYDROPHOBIC POLYMERS
    Kumar, S. Kiran
    Ramarao, T.
    Bikshapathi, D. B. R. N.
    Jayaveera, K. N.
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2013, 4 (01): : 506 - 511
  • [46] EVALUATION OF MOI GUM IN THE FORMULATION OF CONTROLLED RELEASE MATRIX TABLETS USING LOSARTAN POTASSIUM
    Eswaramma, P.
    Murthy, K. V. Ramana
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2019, 10 (01): : 121 - 129
  • [47] Formulation Development and In Vitro Evaluation of Controlled Release Matrix Tablet of Etodolac
    Panchal, Krishna K.
    Chotai, Narendra P.
    INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH, 2013, 47 (04) : 39 - 48
  • [48] Formulation and evaluation of hydroxypropyl methylcellulose-based controlled release matrix tablets for theophylline
    Sekharan, T. Raja
    Palanichamy, S.
    Tamilvanan, S.
    Shanmuganathan, S.
    Thirupathi, A. Thanga
    INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2011, 73 (04) : 451 - 455
  • [49] Formulation and In-vitro Evaluation of Bilayered Buccal Tablets of Carvedilol
    Pandey, Sonia
    Gupta, Arti
    Yadav, Jitendra Singh
    Shah, D. R.
    INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH, 2010, 44 (03) : 259 - 266
  • [50] FORMULATION AND IN-VITRO EVALUATION OF FAST DISSOLVING TABLETS OF GEFITINIB
    Mahboob, Mohd.
    Khabita, Amarah Khan Mariya
    Ali, Sayada Mahewish
    Babu, M. Suresh
    INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2015, 2 (06): : 1048 - 1056
12345