Polyelectrolyte films boost progenitor cell differentiation into endothelium-like monolayers

被引：30
作者：
Berthelemy, Nicolas [1 ]
Kerdjoudj, Halima [1 ]
Gaucher, Caroline [1 ]
Schaaf, Pierre [2 ]
Stolz, Jean-Francois [1 ]
Lacolley, Patrick [3 ]
Voegel, Jean-Claude [4 ]
Menu, Patrick [1 ]
机构：
[1] UHP Nancy 1, Fac Med, LEMTA UMR CNRS 7563, Bioengn Grp, F-54505 Vandoeuvre Les Nancy, France
[2] Inst Charles Sadron, UPR 22, CNRS, F-67083 Strasbourg, France
[3] UHP Nancy 1, Fac Med, Inst Natl Sante & Rech Med, INSERM,U684, F-54505 Vandoeuvre Les Nancy, France
[4] ULP Strasbourg, Fac Chirug Dentaire, INSERM, Inst Natl Sante & Rech Med,U595, F-67085 Strasbourg, France
来源：
ADVANCED MATERIALS | 2008年 / 20卷 / 14期
关键词：
D O I：
10.1002/adma.200702418
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Rapid differentiation of endothelial progenitor cells (EPCs) into confluent mature endothelial cells (see figure) is important in tissue engineering for the design of autologous, nonthrombotic, vascular grafts. A new method based on EPC culture on poly(sodium-4styrene-sulfonate)/poly(allylamine hydrochloride), that is, polyelectrolyte-multilayer-coated substrates, reduces the time from two months to two weeks.
引用
收藏
页码：2674 / +
页数：6
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