Herpes Virus Infections During Treatment With Etanercept in Juvenile Idiopathic Arthritis

被引:6
|
作者
Nicolai, R. [1 ]
Cortis, E. [4 ]
Rava, L. [3 ]
Bracaglia, C. [1 ]
Pardeo, M. [1 ]
Insalaco, A. [1 ]
Buonuomo, P. S. [2 ]
Tozzi, A. E. [3 ]
De Benedetti, F. [1 ]
机构
[1] Bambino Gesu Pediat Hosp, Dept Pediat Med, IRCCS, Div Rheumatol, Piazza St Onofrio 4, I-00165 Rome, Italy
[2] Bambino Gesu Pediat Hosp, Dept Pediat Med, Ist Ricovero & Cura Carattere Sci, Div Rare Dis, Rome, Italy
[3] Bambino Gesu Pediat Hosp, Div Epidemiol, Ist Ricovero & Cura Carattere Sci, Rome, Italy
[4] Osped Santa Maria Stella, Div Pediat, Orvieto, Italy
关键词
etanercept; herpes simplex virus; juvenile idiopathic arthritis; varicella zoster virus; RHEUMATOID-ARTHRITIS; SAFETY; EFFICACY; REGISTRY; CHILDREN; THERAPY;
D O I
10.1093/jpids/piu078
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Incidence rates for varicella and herpes zoster were similar in patients with juvenile idiopathic arthritis receiving etanercept/methotrexate (n = 85, 184.9 patient-years [PY]) or methotrexate alone (n = 71, 199.4 PY); no complicated varicella or herpes zoster cases were reported; herpes labialis incidence was higher in patients receiving etanercept/methotrexate versus methotrexate alone (0.38 vs 0.24 PY).
引用
收藏
页码:76 / 79
页数:4
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