Application of AM SURE™ resin to solid-phase peptide synthesis

被引：13

作者：

Lee, TK

Lee, SM

Ryoo, SJ

Byun, JW

Lee, YS ^{[1
]}

机构：

[1] Seoul Natl Univ, Sch Chem & Biol Engn, Seoul 151744, South Korea

[2] Seoul Natl Univ, Inst Chem Proc, BeadTech Inc, Seoul 151744, South Korea

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 42期

关键词：

core-shell type; aminomethyl polystyrene resin; solid-phase peptide synthesis;

D O I：

10.1016/j.tetlet.2005.08.093

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A core-shell structure was found in AM SURETM resin, in which most amino groups were located at the skin layer. The AM SURETM resin revealed better synthetic efficiency, compared to the noncore-shell type resin in the synthesis of the fragment 6574 of acyl carrier protein, the fragment 27-35 of HIV (human immunodeficiency virus) fusion inhibitor (T-20) and the Jung-Redemann 10-mer. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：7135 / 7138

页数：4

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