Botulinum toxin injections do not improve freezing of gait in Parkinson disease

被引：34
|
作者：
Wieler, M
Camicioli, R
Jones, A
Martin, WRW
机构：
[1] Univ Alberta, Dept Med Neurol, Edmonton, AB, Canada
[2] Univ Alberta, Dept Phys Therapy & Publ Hlth Sci, Edmonton, AB, Canada
来源：
NEUROLOGY | 2005年 / 65卷 / 04期
关键词：
D O I：
10.1212/01.wnl.0000172930.63669.c8
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Freezing of gait ( FOG) is common in patients with Parkinson disease (PD) and responds poorly to medical treatment. Botulinum toxin A (BTX-A) injections into calf muscles decreased FOG in previous open-label studies. The authors conducted a randomized double-blind placebo-controlled crossover study of BTX-A vs placebo in 12 subjects with PD and FOG. No significant improvement with BTX-A was found using subjective and objective measures.
引用
收藏
页码：626 / 628
页数：3
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