ICSBP promoter methylation in myelodysplastic syndromes and acute myeloid leukaemia

被引：8
作者：
Otto, N. [1 ]
Manukjan, G. [1 ]
Goehring, G. [1 ]
Hofmann, W. [1 ]
Scherer, R. [2 ]
Luna, J. Chacon [1 ]
Lehmann, U. [3 ]
Ganser, A. [4 ]
Welte, K. [5 ]
Schlegelberger, B. [1 ]
Steinemann, D. [1 ]
机构：
[1] Hannover Med Sch, Inst Cell & Mol Pathol, D-3000 Hannover, Germany
[2] Hannover Med Sch, Inst Biometry, D-3000 Hannover, Germany
[3] Hannover Med Sch, Inst Pathol, D-3000 Hannover, Germany
[4] Hannover Med Sch, Dept Haematol Haemostasis Oncol & Stem Cell Trans, D-3000 Hannover, Germany
[5] Hannover Med Sch, Ctr Paediat & Adolescent Med & Dermatol, D-3000 Hannover, Germany
来源：
LEUKEMIA | 2011年 / 25卷 / 07期
关键词：
SEQUENCE-BINDING-PROTEIN; MYELOGENOUS LEUKEMIA; CELLS; EXPRESSION; GENE; APOPTOSIS; TRANSCRIPTION; SURVIVAL; MUTATION; MICE;
D O I：
10.1038/leu.2011.61
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
[No abstract available]
引用
收藏
页码：1202 / 1207
页数：6
相关论文
共 21 条
  • [1] Gene-expression profiling identifies distinct subclasses of core binding factor acute myeloid leukemia
    Bullinger, Lars
    Ruecker, Frank G.
    Kurz, Stephan
    Du, Juan
    Scholl, Claudia
    Sander, Sandrine
    Corbacioglu, Andrea
    Lottaz, Claudio
    Froehling, Juergen
    Ganser, Arnold
    Schlenk, Richard F.
    Doehner, Konstanze
    Pollack, Jonathan R.
    Doehner, Hartmut
    [J]. BLOOD, 2007, 110 (04) : 1291 - 1300
  • [2] Quantitative DNA methylation predicts survival in adult acute myeloid leukemia
    Bullinger, Lars
    Ehrich, Mathias
    Doehner, Konstanze
    Schlenk, Richard F.
    Doehner, Hartmut
    Nelson, Matthew R.
    van den Boom, Dirk
    [J]. BLOOD, 2010, 115 (03) : 636 - 642
  • [3] Interferon consensus sequence binding protein (ICSBP; IRF-8) antagonizes BCR/ABL and down-regulates bcl-2
    Burchert, A
    Cai, D
    Hofbauer, LC
    Samuelsson, MKR
    Slater, EP
    Duyster, J
    Ritter, M
    Hochhaus, A
    Müller, R
    Eilers, M
    Schmidt, M
    Neubauer, A
    [J]. BLOOD, 2004, 103 (09) : 3480 - 3489
  • [4] AN INTERFERON GAMMA-REGULATED PROTEIN THAT BINDS THE INTERFERON-INDUCIBLE ENHANCER ELEMENT OF MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I GENES
    DRIGGERS, PH
    ENNIST, DL
    GLEASON, SL
    MAK, WH
    MARKS, MS
    LEVI, BZ
    FLANAGAN, JR
    APPELLA, E
    OZATO, K
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (10) : 3743 - 3747
  • [5] Regulation of apoptosis in myeloid cells by interferon consensus sequence-binding protein
    Gabriele, L
    Phung, J
    Fukumoto, J
    Segal, D
    Wang, IM
    Giannakakou, P
    Giese, N
    Ozata, K
    Morse, HC
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 190 (03) : 411 - 421
  • [6] Rapid and sensitive detection of CpG-methylation using methyl-binding (MB)-PCR
    Gebhard, Claudia
    Schwarzfischer, Lucia
    Pham, Thu Hang
    Andreesen, Reinhard
    Mackensen, Andreas
    Rehli, Michael
    [J]. NUCLEIC ACIDS RESEARCH, 2006, 34 (11) : e82
  • [7] A truncated IFN-regulatory factor-8\IFN consensus sequence-binding protein acts as dominant-negative, interferes with endogenous protein-protein interactions and leads to apoptosis of immune cells
    Hashmueli, S
    Gleit-Kielmanowicz, M
    Meraro, D
    Azriel, A
    Melamed, D
    Levi, BZ
    [J]. INTERNATIONAL IMMUNOLOGY, 2003, 15 (07) : 807 - 815
  • [8] Extrinsic signals determine myeloid-erythroid lineage switch in MN1 leukemia
    Heuser, Michael
    Park, Gyeongsin
    Moon, Yeonsook
    Berg, Tobias
    Xiang, Ping
    Kuchenbauer, Florian
    Vollett, Sarah
    Lai, Courteney
    Humphries, R. Keith
    [J]. EXPERIMENTAL HEMATOLOGY, 2010, 38 (03) : 174 - 179
  • [9] Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene
    Holtschke, T
    Lohler, J
    Kanno, Y
    Fehr, T
    Giese, N
    Rosenbauer, F
    Lou, J
    Knobeloch, KP
    Gabriele, L
    Waring, JF
    Bachmann, MF
    Zinkernagel, RM
    Morse, HC
    Ozato, K
    Horak, I
    [J]. CELL, 1996, 87 (02) : 307 - 317
  • [10] PU.1, interferon regulatory factor (IRF) 2, and the interferon consensus sequence-binding protein (ICSBP/IRF8) cooperate to activate NF1 transcription in differentiating myeloid cells
    Huang, Weiqi
    Horvath, Elizabeth
    Eklund, Elizabeth A.
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (09) : 6629 - 6643
123