Cardiac Transplantation in HIV-Positive Patients: A Narrative Review

被引：0

作者：

Wairimu, Faith ^{[1
]}

Ward, Natalie C. ^{[2
,3
]}

Liu, Yingwei ^{[3
]}

Dwivedi, Girish ^{[1
,2
,3
]}

机构：

[1] Fiona Stanley Hosp, Harry Perkins Inst Med Res, Perth, WA, Australia

[2] Univ Western Australia, Sch Med, Perth, WA, Australia

[3] Univ Ottawa, Univ Ottawa Heart Inst, Div Cardiol, Ottawa, ON, Canada

来源：

JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES | 2021年 / 87卷 / 02期

关键词：

cardiovascular disease; HIV; cardiac transplant; HUMAN-IMMUNODEFICIENCY-VIRUS; ORTHOTOPIC LIVER-TRANSPLANTATION; ANTIRETROVIRAL THERAPY; INFECTED PATIENTS; HEART-FAILURE; HEPATITIS-C; INTERNATIONAL SOCIETY; OUTCOMES; REGISTRY; TACROLIMUS;

D O I：

暂无

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Before the introduction of highly active antiretroviral therapy, patients infected with HIV experienced poor prognosis including high rates of opportunistic infections, rapid progression to AIDS, and significant mortality. Increased life expectancy after therapeutic improvements has led to an increase in other chronic diseases for these patients, including cardiovascular disease and, in particular, end-stage heart failure. Historically, HIV infection was deemed an absolute contraindication for transplantation. Since the development of highly active antiretroviral therapy, however, life expectancy for HIV-positive patients has significantly improved. In addition, there is a low incidence of opportunistic infections and the current antiretrovirals have an improved toxicity profile. Despite this, the current status of cardiac transplants in HIV-positive patients remains unclear. With this in mind, we conducted a narrative review on cardiac transplantation in patients with HIV.

引用

页码：763 / 768

页数：6

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