N-Heterocyclic Carbene (NHC)-Catalyzed All-Carbon [4+2] Cycloaddition-Decarboxylation

被引：20

作者：

Ryan, Sarah ^{[1
]}

Candish, Lisa ^{[1
]}

Lupton, David W. ^{[1
]}

机构：

[1] Monash Univ, Sch Chem, Clayton, Vic 3800, Australia

来源：

SYNLETT | 2011年 / 16期

基金：

澳大利亚研究理事会;

关键词：

catalysis; acyl azolium; N-heterocyclic carbenes; cycloaddition; cyclohexadiene; CATALYZED MICHAEL ADDITION; ALPHA; BETA-UNSATURATED ALDEHYDES; STEREOSELECTIVE-SYNTHESIS; NUCLEOPHILIC CARBENES; GAMMA-BUTYROLACTONES; DIRECT ANNULATIONS; CARBOXYLIC-ACIDS; ALDOL REACTIONS; NHC CATALYSIS; ESTERS;

D O I：

10.1055/s-0030-1261226

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

NHCs activate a diverse range of materials and thereby play a central role in modern reaction discovery. Our studies have focused on the application of NHCs as Lewis base catalysts. We recently developed an all-carbon [4+2] cycloaddition-decarboxylation that typifies this type of catalysis. Herein, the discovery of this methodology, its context and scope are discussed.

引用

页码：2275 / 2278

页数：4

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