N-Heterocyclic Carbene (NHC)-Catalyzed All-Carbon [4+2] Cycloaddition-Decarboxylation

被引：20
|
作者：
Ryan, Sarah [1 ]
Candish, Lisa [1 ]
Lupton, David W. [1 ]
机构：
[1] Monash Univ, Sch Chem, Clayton, Vic 3800, Australia
来源：
SYNLETT | 2011年 / 16期
基金：
澳大利亚研究理事会;
关键词：
catalysis; acyl azolium; N-heterocyclic carbenes; cycloaddition; cyclohexadiene; CATALYZED MICHAEL ADDITION; ALPHA; BETA-UNSATURATED ALDEHYDES; STEREOSELECTIVE-SYNTHESIS; NUCLEOPHILIC CARBENES; GAMMA-BUTYROLACTONES; DIRECT ANNULATIONS; CARBOXYLIC-ACIDS; ALDOL REACTIONS; NHC CATALYSIS; ESTERS;
D O I：
10.1055/s-0030-1261226
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
NHCs activate a diverse range of materials and thereby play a central role in modern reaction discovery. Our studies have focused on the application of NHCs as Lewis base catalysts. We recently developed an all-carbon [4+2] cycloaddition-decarboxylation that typifies this type of catalysis. Herein, the discovery of this methodology, its context and scope are discussed.
引用
收藏
页码：2275 / 2278
页数：4
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