Magnetic Resonance Imaging of Malformations of Cortical Development-A Comprehensive Review

被引：0

作者：

Khandelwal, Ayush ^{[1
,2
]}

Aggarwal, Ankita ^{[1
,2
,3
]}

Sharma, Anuradha ^{[1
,2
]}

Malik, Amita ^{[1
,2
]}

Bose, Anindita ^{[1
,2
]}

Aggarwal, Ankita ^{[1
,2
,3
]}

机构：

[1] VMMC, Dept Radiol, Delhi, India

[2] Safdarjang Hosp, Delhi, India

[3] UCMS & GTB Hosp, Delhi, India

来源：

WORLD NEUROSURGERY | 2022年 / 159卷

关键词：

Cortical development; Developmental delay; Epilepsy; Heterotopia; Malformation; BILATERAL PERISYLVIAN SYNDROME; SUBCORTICAL HETEROTOPIA; GENETIC CLASSIFICATION; DISORDERS; POLYMICROGYRIA; DYSPLASIA; FEATURES; BRAIN; APPEARANCE; MUTATIONS;

D O I：

10.1016/J.WNEu.2021.12.011

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Malformations of cortical development (MCDs) are structural anomalies that disrupt the normal process of cortical development. These include microcephaly with simplified gyral pattern/microlissencephaly, hemimegalencephaly, focal cortical dysplasia, lissencephaly, heterotopia, polymicrogyria, and schizence-phaly. They can present with intractable epilepsy, developmental delay, neuro-logic deficits, or cognitive impairment. Though the definitive diagnosis of MCD depends on histopathology, the pathologic tissue is rarely available; hence diagnosis begins with neuroimaging. This article shall briefly review the embryology, followed by specific magnetic resonance imaging features of MCD in an attempt to simplify the process of diagnosing these disorders with clinical and genetic correlation. A table has been included to highlight the embryologic, clinical, and genetic findings associated with various MCDs.

引用

页码：70 / 79

页数：10

共 58 条

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