Asymmetric Hydrosilylation of Aromatic Ketones Catalyzed by an Economical and Effective Copper-Diphosphine Catalytic System in Air

被引：8

作者：

Liang, Minting ^{[1
]}

Xia, Xiaofeng ^{[1
]}

Liu, Xiang ^{[1
]}

Li, Hexing ^{[2
]}

机构：

[1] Jiangnan Univ, Sch Chem & Mat Engn, Minist Educ, Key Lab Food Colloids & Biotechnol, Wuxi 214122, Jiangsu, Peoples R China

[2] Shanghai Normal Univ, Chinese Minist Educ Resource Chem, Key Lab, Shanghai 200234, Peoples R China

来源：

CHINESE JOURNAL OF CHEMISTRY | 2015年 / 33卷 / 05期

基金：

中国国家自然科学基金;

关键词：

asymmetric catalysis; hydrosilylation; ketones; copper salt; polymethylhydrosiloxane; EFFICIENT ENANTIOSELECTIVE HYDROSILYLATION; CONJUGATE REDUCTION; COPPER(II)-DIPYRIDYLPHOSPHINE CATALYST; SELECTIVE HYDROSILYLATION; HETEROARYL KETONES; COMPLEXES; LIGANDS; ARYL; HYDROGENATION; RHODIUM;

D O I：

10.1002/cjoc.201500072

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the presence of the inexpensive and non-toxic polymethylhydrosiloxane, the combination of copper(II) acetate and a chiral diphosphine displayed high catalytic efficiency in the asymmetric hydrosilylation of a series of aromatic ketones in air atmosphere and at room temperature. (R)-1-Arylethanols were obtained with up to 99% yield and 93% enantiomeric excess. Meanwhile, the electron effect and steric hindrance of substituents on the aromatic ring had an interesting influence on both the yields and enantioselectivities. Furthermore, a possible mechanism was presented to explain the influence of some key factors on the reaction.

引用

页码：578 / 582

页数：5

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