A mapping platform for mitotic crossover by single-cell multi-omics

被引：1

作者：

Chovanec, Peter ^{[1
]}

Yin, Yi ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Dept Human Genet, Los Angeles, CA 90095 USA

来源：

DNA REPLICATION-REPAIR INTERFACE | 2021年 / 661卷

基金：

美国国家卫生研究院;

关键词：

GENOME-WIDE; MUTATIONAL SIGNATURES; STRAND BREAKS; END RESECTION; INSTABILITY; REPAIR; RECOMBINATION;

D O I：

10.1016/bs.mie.2021.08.017

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Mitotic crossovers have the potential to cause large-scale genome rearrangements. Here, we describe high-throughput, single-cell, whole-genome sequencing methods for mapping crossovers genome-wide at scale. The methods are generalizable to various eukaryotes and to other end points requiring high-throughput, high-coverage single cell sequencing.

引用

页码：183 / 204

页数：22

共 50 条

[21] The technological landscape and applications of single-cell multi-omics
Alev Baysoy
Zhiliang Bai
Rahul Satija
Rong Fan
Nature Reviews Molecular Cell Biology, 2023, 24 : 695 - 713
[22] Clustering single-cell multi-omics data with MoClust
Yuan, Musu
Chen, Liang
Deng, Minghua
BIOINFORMATICS, 2023, 39 (01)
[23] How single-cell multi-omics builds relationships
Vivien Marx
Nature Methods, 2022, 19 : 142 - 146
[24] Intricacies of single-cell multi-omics data integration
Rautenstrauch, Pia
Vlot, Anna Hendrika Cornelia
Saran, Sepideh
Ohler, Uwe
TRENDS IN GENETICS, 2022, 38 (02) : 128 - 139
[25] Applications of single-cell multi-omics in liver cancer
Peeters, Frederik
Cappuyns, Sarah
Pique-Gili, Marta
Phillips, Gino
Verslype, Chris
Lambrechts, Diether
Dekervel, Jeroen
JHEP REPORTS, 2024, 6 (07)
[26] Single Cell Atlas: a single-cell multi-omics human cell encyclopedia
Pan, Lu
Parini, Paolo
Tremmel, Roman
Loscalzo, Joseph
Lauschke, Volker
Maron, Bradley
Paci, Paola
Ernberg, Ingemar
Tan, Nguan Soon
Liao, Zehuan
Yin, Weiyao
Rengarajan, Sundararaman
Li, Xuexin
GENOME BIOLOGY, 2024, 25 (01)
[27] Multi-Omics and Single-Cell Omics: New Tools in Drug Target Discovery
Loscalzo, Joseph
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2024, 44 (04) : 759 - 762
[28] Medicinal plants enter the single-cell multi-omics era
Burlat, Vincent
Papon, Nicolas
Courdavault, Vincent
TRENDS IN PLANT SCIENCE, 2023, 28 (11) : 1205 - 1207
[29] Benchmarking algorithms for single-cell multi-omics prediction and integration
Hu, Yinlei
Wan, Siyuan
Luo, Yuanhanyu
Li, Yuanzhe
Wu, Tong
Deng, Wentao
Jiang, Chen
Jiang, Shan
Zhang, Yueping
Liu, Nianping
Yang, Zongcheng
Chen, Falai
Li, Bin
Qu, Kun
NATURE METHODS, 2024, 21 (11) : 2182 - +
[30] Paired single-cell multi-omics data integration with Mowgli
Huizing, Geert-Jan
Deutschmann, Ina Maria
Peyre, Gabriel
Cantini, Laura
NATURE COMMUNICATIONS, 2023, 14 (01)

← 1 2 3 4 5 →