Regulatory issues surrounding the use of companion animals in clinical investigations, trials, and studies

被引:13
作者
Hampshire, VA [1 ]
机构
[1] Adv Vet Applicat, Bethesda, MD USA
关键词
companion animal research; regulatory affairs; veterinary clinical research; veterinary drugs; veterinary vaccines;
D O I
10.1093/ilar.44.3.191
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Laboratory animal veterinarians sometimes encounter animals with rare conditions and may subsequently become involved in the performance of related animal research outside the laboratory, in homes, in veterinary clinics, or in universities to which owners have donated their animals for study. Similarly, veterinarians may monitor animal companion vaccination studies, performed to optimize preventive health care or minimize physiological variability and research confounders associated with a preventive medicine program for dogs and cats utilized for research procedures. These nontraditional uses of dogs, cats, and other companion animals in research have spurred the establishment of regulations to ensure that the animals benefit from clinical veterinary products and techniques. Included and described are the 2002 Public Health Service Policy, the Animal Welfare Act (AWA), the Federal Food, Drug, and Cosmetic Act, and the regulations of the US Department of Agriculture in response to the AWA. The complexities of clinical research with companion animals outside standard biomedical research facilities are discussed.
引用
收藏
页码:191 / 196
页数:6
相关论文
共 16 条
  • [1] *AAFP, 2000, 2000 AAFP
  • [2] *APPMA, 2002, 2001 2002 NAT PET OW
  • [3] DAVIS TC, 1998, J NATL CANCER I, P90668
  • [4] *FDA, 1989, 33 US FDA
  • [5] *FDA, 2001, 85 US FDA
  • [6] *FDA, 1997, 58 USF FDA
  • [7] Gaskell RM, 2002, VET REC, V150, P126
  • [8] HOMESROVNER M, 2002, MED CARE, V49, P30
  • [9] IRAC,, 1985, US GOV PRINC UT CAR
  • [10] LANTOS J, 1993, CANC S, V172, P2811