Role of γδ T cells in West Nile virus-induced encephalitis: Friend or foe?

被引：10
|
作者：
Wang, Tian [1 ]
机构：
[1] Univ Texas Med Branch, Dept Microbiol & Immunol, Galveston, TX 77555 USA
来源：
JOURNAL OF NEUROIMMUNOLOGY | 2011年 / 240卷
关键词：
West Nile virus; Encephalitis; Gamma/delta T cells; CENTRAL-NERVOUS-SYSTEM; ADAPTIVE IMMUNE-RESPONSE; TOLL-LIKE RECEPTOR-3; LETHAL ENCEPHALITIS; DENDRITIC CELLS; FAS LIGAND; IN-VITRO; RIG-I; INFECTION; MICE;
D O I：
10.1016/j.jneuroim.2011.10.004
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
West Nile virus (WNV)-induced encephalitis has been a public health concern in North America over the past decade. No therapeutics or vaccines are available for human use. Studies in animal models have provided important information for investigations of WNV pathogenesis and the host immune response in humans. This article will give an overview of the role of gamma delta T cells, one of the non-classical T cell subsets in the murine model of WNV encephalitis. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码：22 / 27
页数：6
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