Association between liver targeted antiviral therapy in colorectal cancer and survival benefits: An appraisal

被引：2
作者：
Wang, Qiang [1 ]
Yu, Chao-Ran [1 ]
机构：
[1] Fudan Univ, Shanghai Canc Ctr, Dept Oncol, Shanghai Med Coll, 270 Dongan Rd, Shanghai 200025, Peoples R China
来源：
WORLD JOURNAL OF CLINICAL CASES | 2020年 / 8卷 / 11期
关键词：
Colorectal cancer; Liver metastasis; Antiviral therapy; Survival; Injury status; Biomarkers; HEPATITIS-B-VIRUS; HEPATOCELLULAR-CARCINOMA; METASTASES; BLOCKADE;
D O I：
10.12998/wjcc.v8.i11.2111
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In colorectal cancer (CRC), liver metastasis remains a major contributor to the cause of cancer-related death. Putative biomarkers, therapeutic efficacy, and drug insensitivity still pose clinical challenges for metastatic CRC patients. Interestingly, previous studies indicated that tumor cells in CRC did not metastasize to the injured liver, which included hepatitis or cirrhotic liver. The benefits of antiviral therapy on hepatocellular carcinoma have also been identified. This review discusses the role of antiviral therapy on the liver. Antiviral therapy may reduce potential liver metastasis associated with CRC in several mechanistic aspects.
引用
收藏
页码：2111 / 2115
页数：6
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