Antithrombotic properties of sulfated wood-derived galactoglucomannans

被引：18
|
作者：
Doliska, Ales [1 ]
Willfor, Stefan [3 ]
Strnad, Simona [1 ]
Ribitsch, Volker [2 ]
Kleinschek, Karin Stana [1 ]
Eklund, Patrik [4 ]
Xu, Chunlin [3 ]
机构：
[1] Univ Maribor, Fac Mech Engn, Inst Engn Mat & Design, Maribor, Slovenia
[2] Graz Univ, Inst Chem, A-8010 Graz, Austria
[3] Abo Akad Univ, Proc Chem Ctr, Lab Wood & Paper Chem, Turku, Finland
[4] Abo Akad Univ, Proc Chem Ctr, Organ Chem Lab, Turku, Finland
来源：
HOLZFORSCHUNG | 2012年 / 66卷 / 02期
基金：
芬兰科学院;
关键词：
activated partial thromboplastin time; anticoagulant; antithrombocity; carboxymethylation; galactoglucomannan; spruce wood; sulfated polysaccharide; FLUORESCENT INDICATOR; ANTICOAGULANT; GALACTOMANNANS; EXTRACTION; TITRATION; PULP;
D O I：
10.1515/HF.2011.136
中图分类号：
S7 [林业];
学科分类号：
0829 ; 0907 ;
摘要：
Galactoglucomannans (GGMs) are water-soluble polysaccharides released and accumulated in process waters in the production of thermomechanical pulp. The general trend in the forestry industry is moving towards bio-refineries, for example utilizing these hemicelluloses as bioactive substances. At present, there is no industrial use of wood-derived mannans. In this study, GGMs extracted from thermomechanical pulp, as well as further carboxymethylated galactoglucomannans (CM-GGMs), were sulfated to increase their antithrombotic properties. The products were characterized with Fourier transform infrared spectroscopy, nuclear magnetic resonance and capillary electrophoresis. The carbohydrate composition and sulfur amounts were determined. The products' total charges were determined by polyelectrolyte titrations and their antithrombotic effect was measured based on the activated partial thromboplastin time. The results showed a significant increase in the antithrombotic effect of the sulfated galactoglucomannans from spruce wood and thus a potential new use for wood-derived mannans.
引用
收藏
页码：149 / 154
页数：6
相关论文
共 50 条
  • [31] UPGRADING OF A WOOD-DERIVED OIL OVER VARIOUS CATALYSTS
    ADJAYE, JD
    BAKHSHI, NN
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1993, 205 : 58 - CELL
  • [32] Wood-Derived Nanopaper Dielectrics for Organic Synaptic Transistors
    Dai, Shilei
    Wang, Yan
    Zhang, Junyao
    Zhao, Yiwei
    Xiao, Feipeng
    Liu, Dapeng
    Wang, Tengrui
    Huang, Jia
    ACS APPLIED MATERIALS & INTERFACES, 2018, 10 (46) : 39983 - 39991
  • [33] Wood-Derived Monolithic Carbon Materials and Their Functional Applications
    Sun, Yating
    He, Zhaocai
    Wei, Yuan
    Liu, Gonggang
    Liu, Rukuan
    Hu, Jinbo
    Liu, Huaifei
    Zhang, Xiang
    Yuan, Guangming
    CLEAN-SOIL AIR WATER, 2022, 50 (06)
  • [34] Thermal properties of wood-derived copper-silicon carbide composites fabricated via electrodeposition
    Pappacena, K. E.
    Johnson, M. T.
    Wang, H.
    Porter, W. D.
    Faber, K. T.
    COMPOSITES SCIENCE AND TECHNOLOGY, 2010, 70 (03) : 478 - 484
  • [35] Effect of Dewatering Wood-Derived Fast Pyrolysis Oil on Its Fuel Properties for Power Generation
    Khan, Muhammad Shahzeb
    Rafiq, Maira
    Sookrah, Vijai
    Thomson, Murray J.
    ENERGY & FUELS, 2019, 33 (12) : 12403 - 12420
  • [36] Mechanical properties of wood-derived silicon carbide aluminum-alloy composites as a function of temperature
    T.E. Wilkes
    J.Y. Pastor
    J. Llorca
    K.T. Faber
    Journal of Materials Research, 2008, 23 : 1732 - 1743
  • [37] Mechanical properties of wood-derived silicon carbide aluminum-alloy composites as a function of temperature
    Wilkes, T. E.
    Pastor, J. Y.
    Llorca, J.
    Faber, K. T.
    JOURNAL OF MATERIALS RESEARCH, 2008, 23 (06) : 1732 - 1743
  • [38] Genotoxicity evaluation of wood-derived and vegetable oil-derived stanol esters
    Turnbull, D
    Frankos, VH
    van Delft, JHM
    DeVogel, N
    REGULATORY TOXICOLOGY AND PHARMACOLOGY, 1999, 29 (02) : 205 - 210
  • [39] Ecological objectives can be achieved with wood-derived bioenergy Reply
    Schlesinger, William H.
    FRONTIERS IN ECOLOGY AND THE ENVIRONMENT, 2015, 13 (06) : 299 - 299
  • [40] PYROLYSIS OF A WOOD-DERIVED MATERIAL - EFFECTS OF MOISTURE AND ASH CONTENT
    GRAY, MR
    CORCORAN, WH
    GAVALAS, GR
    INDUSTRIAL & ENGINEERING CHEMISTRY PROCESS DESIGN AND DEVELOPMENT, 1985, 24 (03): : 646 - 651
12345