A Novel Case of Concurrent T-cell and Early T-cell Precursor Lymphoblastic Lymphoma in an Adolescent Female

被引：1

作者：

Treinen, Charles ^{[1
]}

Abu-Arja, Mohammad H. ^{[4
]}

Kahwash, Samir B. ^{[2
]}

Rangarajan, Hemalatha G. ^{[1
,3
]}

Willen, Faye ^{[1
]}

Audino, Anthony N. ^{[1
,3
]}

机构：

[1] Nationwide Childrens Hosp, Div Hematol Oncol Blood & Marrow Transplant, Columbus, OH USA

[2] Nationwide Childrens Hosp, Dept Pathol & Lab Med, Columbus, OH USA

[3] Ohio State Univ, Dept Pediat, Columbus, OH 43210 USA

[4] New York Presbyterian Brooklyn Methodist Hosp, Dept Pediat, Brooklyn, NY USA

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2022年 / 44卷 / 02期

关键词：

early T-cell precursor lymphoblastic lymphoma; hematopoietic stem cell transplant; multiagent intense chemotherapy; T-cell lymphoblastic leukemia; lymphoma; MINIMAL RESIDUAL DISEASE; LEUKEMIA; LEUKEMIA/LYMPHOMA; CHILDREN; SUBTYPE; ADULTS;

D O I：

10.1097/MPH.0000000000002257

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In the context of an evolving understanding of early T-cell precursor (ETP) lymphoma and leukemia, we present a case of concurrent T-cell lymphoblastic lymphoma and ETP lymphoma in an adolescent female. To our knowledge, this represents the first reported case of both lymphoblastic lymphoma and ETP lymphoma as distinct and conjoined components of the same neoplasm. As an exception to current literature, our patient had a strictly lymphomatous ETP component with no leukemic manifestation. Her ETP component remained viable following induction, supporting ETP resistance to chemotherapy. The patient remains in remission 4 years postallogeneic matched sibling donor bone marrow transplant.

引用

页码：E550 / E553

页数：4

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